Results 51 to 60 of about 1,452 (123)

Inositol With Metformin Versus Metformin Monotherapy in Polycystic Ovary Syndrome: A Meta‐Analysis of Randomised Controlled Trials

Reproductive, Female and Child Health, Volume 4, Issue 3, September 2025.
ABSTRACT Background The effectiveness of the combination of metformin and inositol versus metformin on clinical and laboratory results in patients with polycystic ovary syndrome (PCOS) is not well known. Objectives We aimed to compare the use of inositol with metformin versus metformin in patients with PCOS. Search Strategy PubMed, Embase, and Cochrane
Milene Vitória Sampaio Sobral, Victor Gonçalves Soares, Hilária Saugo Faria, Lucas Cael Azevedo Ramos Bendaham, Barbara Bombassaro Masiero, Ocilio de Deus da Rocha Ribeiro Gonçalves, Fernando Augusto Barreiros, Marina Ayabe Gomes de Moraes   +7 more
wiley   +1 more source

The effect of inositol on the content of oxidative modified proteins in the liver and heart of different sexes rats with metabolic associated steatotic liver disease

Journal of V. N. Karazin Kharkiv National University: Series Medicine
Background. The problem of metabolic disorders and, in particular, metabolically associated steatotic hepatic disease (MASHD) is one of the most relevant today.
Sopel O.V., Levchuk O.O., Denefil O.V.
doaj   +1 more source

Nutraceutical prospective: The synergetic mechanism of action of inositols and resveratrol on metabolic syndrome

The EuroBiotech Journal, 2018
It has been known that inositols function as insulin second messengers and mediate different insulin-dependent processes and are a valid natural, non-pharmaceutical alternative to contrast insulin-resistance as well as associated metabolic syndrome in ...
Malvasi Antonio, Tinelli Andrea, Baldini Domenico, Iannitti Rossana G., Fioretti Bernard   +4 more
doaj   +1 more source

Inositols in Midlife

Journal of Mid-Life Health, 2018
This review describes the mechanistic, animal, and clinical data related to the use of inositols in midlife. It covers studies related to the mechanism of action of myo-inositol and D-chiro-inositol and randomized controlled trials conducted in ...
Sanjay Kalra, Bharti Kalra
doaj   +1 more source

Inositols in reproductive medicine

Репродуктивная эндокринология, 2020
The article presents literature data on the role of inositol and its derivatives in human body, results of the myo-inositol (MI) use in gynecological diseases, treatment of female and male infertility, including in cycles of assisted reproductive ...
O. M. Nosenko, O. V. Novikova
doaj   +1 more source

Provenance Variation in Functional Traits of European Forest Trees: Meta‐Analysis Reveals Effects of Taxa and Age Despite Critical Research Gaps

Ecology and Evolution, Volume 15, Issue 8, August 2025.
This meta‐analysis on intraspecific variation in European trees studied the frequency of provenance variation, provenance–environment interaction, clinal variation along the climate of origin or transfer distance. While identifying trait group specific patterns of variation, research gaps have been identified in terms of age and geographical ...
Samuel Aspalter, Albert Ciceu, Carlos Miguel Landivar Albis, Debojyoti Chakraborty, Silvio Schueler   +4 more
wiley   +1 more source

New Insights Into the Use of Cereals and Pseudocereals in Fermented Beverages: Trends, Challenges, and Innovations

eFood, Volume 6, Issue 4, August 2025.
This review explores cereals and pseudocereals in fermented beverages, highlighting trends, challenges, and innovations supporting health, sustainability, and gluten‐free brewing. ABSTRACT Nowadays, cereals and pseudocereals are crucial in producing fermented drinks, conferring their nutritional, functional, and sensory properties.
Amal Sudaraka Samarasinghe, Fabiola Fernando, Kerthika Devi Athiyappan, Baojun Xu, Abu Saeid   +4 more
wiley   +1 more source

Inositol Restores Appropriate Steroidogenesis in PCOS Ovaries Both In Vitro and In Vivo Experimental Mouse Models

Cells
Androgen excess is a key feature of several clinical phenotypes of polycystic ovary syndrome (PCOS). However, the presence of FSH receptor (FSHR) and aromatase (CYP19A1) activity responses to physiological endocrine stimuli play a critical role in the ...
Valeria Fedeli, Vittorio Unfer, Simona Dinicola, Antonio Simone Laganà, Rita Canipari, Noemi Monti, Alessandro Querqui, Emanuele Galante, Gaia Laurenzi, Mariano Bizzarri   +9 more
doaj   +1 more source

Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials

Endocrine Connections, 2017
Myo-inositol (MI) supplementation in women with polycystic ovary syndrome (PCOS) has been evaluated over the last years. Many hormonal and reproductive impairments associated with this disorder seem relieved by the supplement.
Vittorio Unfer1,, Fabio Facchinetti2,, Beatrice Orrù3,, Barbara Giordani, John Nestler   +4 more
doaj   +1 more source

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

Advanced Biology, Volume 9, Issue 7, July 2025.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua, Cristiano Giuliani, Giovanna Di Emidio, Samuel H Myers, Vittorio Unfer, Carla Tatone   +5 more
wiley   +1 more source