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The emergence of neuroinvasive Cryptococcus: why eucalyptus-rich regions, especially in Africa, may be facing greater risk [PDF]
Frontiers in Cellular and Infection MicrobiologyCryptococcal meningitis (CM) is often approached under the assumption that Cryptococcus neoformans strains from any environment have equal potential for rapid central nervous system (CNS) invasion.
Hilaire Irere +6 more
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Inhibitors of Inositol Monophosphatase [PDF]
Journal of Enzyme Inhibition, 1999 Inositol monophosphatase (IMPase) catalyses the hydrolysis of myo-inositol monophosphates to myo-inositol, which is required in the phosphatidyl inositol cell signalling pathway. Here the enzyme structure, mechanism and inhibition of IMPase are reviewed. Lithium, an effective therapy for manic depression, is an uncompetitive inhibitor.
Fauroux, Christine M J, Freeman, Sally
core +9 more sources
Treatment with Myo-Inositol Does Not Improve the Clinical Features in All PCOS Phenotypes
Biomedicines, 2023 Background: The aim of the present study is to investigate the effects produced by a treatment with myo-Inositol (myo-Ins) in women presenting polycystic ovary syndrome (PCOS) of different phenotypes.
Vittorio Unfer +5 more
doaj +1 more source
Molecules, 2020 (1) Background: Myoinositol (MI) and D-chiro-inositol (DCI) are involved in a number of biochemical pathways within oocytes having a role in oocyte maturation, fertilization, implantation, and post-implantation development. Both inositols have a role in insulin signaling and hormonal synthesis in the ovaries.
Zdravko Kamenov, Antoaneta Gateva
openaire +3 more sources
Oxidative Stress and Male Fertility: Role of Antioxidants and Inositols
Antioxidants, 2021 Infertility is defined as a couple’s inability to conceive after at least one year of regular unprotected intercourse. This condition has become a global health problem affecting approximately 187 million couples worldwide and about half of the cases are
Maria Nunzia De Luca +4 more
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Scientific Reports, 2023 Accumulating evidence suggests that oral supplementation with myo-Inositol (myo-Ins) is able to reduce the amount of gonadotropins and days of controlled ovarian hyperstimulation (COS) necessary to achieve adequate oocyte maturation in assisted ...
Ariel Beresniak +7 more
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New Insights into the Activities of D-Chiro-Inositol: A Narrative Review
Biomedicines, 2021 D-chiro-inositol (DCI) is a natural compound detectable in cell membranes, which is highly conserved as a biological signaling molecule. In mammals, its function is primarily characterized in the intracellular transduction cascade of insulin.
Riccardo Gambioli +5 more
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The Role of Inositol in Thyroid Physiology and in Subclinical Hypothyroidism Management
Frontiers in Endocrinology, 2021 Myo-Inositol (MYO) is the most abundant stereoisomer of inositols’ family, cyclic polyols with 6 hydroxyl groups. Myo-Inositol has a relevant role in thyroid function and autoimmune diseases, as a precursor of phosphoinositides that takes part in the ...
Salvatore Benvenga +7 more
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Boswellia, inositol and betaine in the treatment of fibroadenoma: a case study [PDF]
International Journal of Medical Device and Adjuvant Treatments, 2020 OBJECTIVE: Nowadays, no completely side effect-free therapeutic approach for mammary fibroadenomas exists, considering that the election therapy is based on antiestrogens, as well as on surgery for more severe cases.
N. Monti, V. Pasta, V. D’Orazi
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