Results 1 to 10 of about 73,117 (195)

PE_PGRS3 ensures provision of the vital phospholipids cardiolipin and phosphatidylinositols by promoting the interaction betweenM. tuberculosisand host cells

Virulence, 2021
PE_PGRS proteins of Mycobacterium tuberculosis (Mtb) constitute a large family of complex modular proteins whose role is still unclear. Among those, we have previously shown, using the heterologous expression in Mycobacterium smegmatis, that PE_PGRS3 ...
Rita Berisio, Silvia Bellesi, Massimiliano Papi   +2 more
exaly   +3 more sources

Differences in levels of phosphatidylinositols in healthy and stable Coronary Artery Disease subjects revealed by HILIC-MRM method with SERRF normalization.

PLoS ONE, 2021
Quantification of endogenous biomarkers in clinical studies requires careful evaluation of a number of assay performance parameters. Comparisons of absolute values from several clinical studies can enable retrospective analyses further elucidating the ...
Yue Huang, Ruipeng Mu, David Wen, Joseph S Grimsby, Meina Liang, Anton I Rosenbaum   +5 more
doaj   +2 more sources

Resolution of intact phosphatidylinositols by argentation thin-layer chromatography

Journal of Lipid Research, 1971
An argentation thin-layer chromatographic method is described for the separation of intact phosphatidylinositols on the basis of the degree of unsaturation of their component fatty acids.
B.J. Holub, A. Kuksis
doaj   +2 more sources

Separation of phosphatidylinositols and other phospholipids by two-step one-dimensional thin-layer chromatography.

Journal of Lipid Research, 1989
A quick and efficient thin-layer chromatographic procedure is described for the separation of phosphatidylinositol-4,5-bisphosphate, phosphatidylinositol-4-monophosphate, phosphatidylinositol, phosphatidylcholine, phosphatidic acid, and ...
J D Medh, P H Weigel
doaj   +2 more sources

Untargeted lipidomics analysis in women with morbid obesity and type 2 diabetes mellitus: A comprehensive study. [PDF]

PLoS ONE
There is a phenotype of obese individuals termed metabolically healthy obese that present a reduced cardiometabolic risk. This phenotype offers a valuable model for investigating the mechanisms connecting obesity and metabolic alterations such as Type 2 ...
Laia Bertran, Jordi Capellades, Sonia Abelló, Carmen Aguilar, Teresa Auguet, Cristóbal Richart   +5 more
doaj   +2 more sources

Lipid Subclasses Differentiate Insulin Resistance by Triglyceride–Glucose Index [PDF]

Metabolites
Background: Insulin resistance is a key driver of metabolic syndrome and related disorders, yet its underlying metabolic alterations remain incompletely understood.
Khaled Naja, Najeha Anwardeen, Omar Albagha, Mohamed A. Elrayess   +3 more
doaj   +2 more sources

Branched-chain amino acids and specific phosphatidylinositols are plasma metabolite pairs associated with menstrual pain severity [PDF]

Scientific Reports
Menstrual pain affects women’s quality of life and productivity, yet objective molecular markers for its severity have not been established owing to the variability in blood levels and chemical properties of potential markers such as plasma steroid ...
Atsushi Sato, Kanako Yuyama, Yuko Ichiba, Yasushi Kakizawa, Yuki Sugiura   +4 more
doaj   +2 more sources

The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes

Biochemical Journal, 1993
Michael A J Ferguson, Ferguson M A J, M A Ferguson   +2 more
exaly   +2 more sources

Characterization of phospholipase C activity at h5-HT 2C compared with h5-HT 2B receptors: influence of novel ligands upon membrane-bound levels of [ 3 H]phosphatidylinositols

Naunyn-Schmiedeberg's Archives of Pharmacology, 2002
Adrian Newman-Tancredi, Didier Cussac, Newman-Tancredi Adrian   +2 more
exaly   +2 more sources

Tuberculostearic Acid-Containing Phosphatidylinositols as Markers of Bacterial Burden in Tuberculosis

ACS Infectious Diseases, 2022
One-fourth of the global human population is estimated to be infected with strains of the Mycobacterium tuberculosis complex (MTBC), the causative agent of tuberculosis (TB). Using lipidomic approaches, we show that tuberculostearic acid (TSA)-containing
Julius Brandenburg, J. Heyckendorf, Franziska Marwitz, Nicole Zehethofer, Lara Linnemann, N. Gisch, H. Karaköse, M. Reimann, K. Kranzer, B. Kalsdorf, Patricia M Sánchez-Carballo, Michael Weinkauf, Verena Scholz, S. Malm, S. Homolka, K. Gaede, C. Herzmann, U. Schaible, Christoph Hölscher, N. Reiling, D. Schwudke   +20 more
semanticscholar   +1 more source