Results 1 to 10 of about 32,392 (245)
Analytical and Bioanalytical Chemistry, 2015 Profiling of the individual lipids in biological fluids is of great concern with respect to human health and disease; as a consequence, the task of lipid analysis and profiling has become ever increasingly important, and lipidomics has become the target ...
Beccaria M. +9 more
core +7 more sources
The EMBO Journal, 2005 The cellular lipidome comprises over 1000 different lipids. Most lipids look similar having a polar head and hydrophobic tails. Still, cells recognize lipids with exquisite specificity.
van Meer, G. +4 more
core +5 more sources
Metabolomics, lipidomics, and immunometabolism
, 2021 Metabolomics, lipidomics, and the study of cellular metabolism are gaining increasing interest particularly in the field of immunology, since the activation and effector functions of immune cells are profoundly controlled by changes in cellular metabolic
Colamatteo A. +8 more
core +4 more sources
, 2013 Lipids are a diverse group of compounds with multiple key biological functions. Lipidomics is a subdiscipline of metabolomics, with the focus on the global study of molecular lipids, including pathways and networks of cellular lipids in biological ...
Pondia Pons, Isabel +3 more
core +4 more sources
Clinica Chimica Acta, 2020 The present article examines recently published literature on lipids, mainly focusing on research involving glycero-, glycerophospho- and sphingo-lipids. The primary aim is identification of distinct profiles in biologic lipidomic systems by ultra-high-performance liquid chromatography (UHPLC) coupled with mass spectrometry (MS, tandem MS) with ...
Henri F. Avela, Heli Sirén
openaire +2 more sources
Analytical and Bioanalytical Chemistry, 2018 The state-of-art in the lipidomic analysis is summarized here to provide the overview of available sample preparation strategies, mass spectrometry (MS)-based methods for the qualitative analysis of lipids, and the quantitative MS approaches for high-throughput clinical workflows.
Michal Holčapek +2 more
openaire +5 more sources
A DMS Shotgun Lipidomics Workflow Application to Facilitate High-Throughput, Comprehensive Lipidomics [PDF]
, 2021 Differential mobility spectrometry (DMS) is highly useful for shotgun lipidomic analysis because it overcomes difficulties in measuring isobaric species within a complex lipid sample and allows for acyl tail characterization of phospholipid species ...
Daniel Hornburg +21 more
core +3 more sources
Lipidomics of Glycosphingolipids [PDF]
Metabolites, 2012 Glycosphingolipids (GSLs) contain one or more sugars that are attached to a sphingolipid moiety, usually to a ceramide, but in rare cases also to a sphingoid base. A large structural heterogeneity results from differences in number, identity, linkage, and anomeric configuration of the carbohydrate residues, and also from structural differences within ...
Farwanah, Hany, Kolter, Thomas
openaire +4 more sources
, 2022 Lipids are historically considered a source of energy and a component of cell membranes. Over the last years, many other functions have been studied, and their importance in our health is well established. For this reason, studies on lipidomics have been
Gomes, Ana Maria +3 more
core +1 more source
Plant Signaling & Behavior, 2011 A wealth of information related to lipid metabolism and signaling has been revealed in recent years using mass spectrometric-based lipidomics methods. Although quantitatively sensitive, these compositional profiling methods rely on conventional tissue extractions of total lipids which results in a loss of original cellular context of lipid metabolites.
Patrick J, Horn, Kent D, Chapman
openaire +2 more sources