Results 1 to 10 of about 51,608 (289)
Analytica Chimica Acta, 2019 The mainstream of lipidomics involves mass spectrometry-based, systematic, and large-scale studies of the structure, composition, and quantity of lipids in biological systems such as organs, cells, and body fluids. As increasingly more researchers in broad fields are beginning to pay attention to and actively learn about the lipidomic technology, some ...
Jianing Wang, Chunyan Wang, Xianlin Han
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Analytical and Bioanalytical Chemistry, 2015 Profiling of the individual lipids in biological fluids is of great concern with respect to human health and disease; as a consequence, the task of lipid analysis and profiling has become ever increasingly important, and lipidomics has become the target of postgenomic research.
DONATO, Paola Agata Eustochia +4 more
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Advanced Drug Delivery Reviews, 2020 Lipids are ubiquitous in the human organism and play essential roles as components of cell membranes and hormones, for energy storage or as mediators of cell signaling pathways. As crucial mediators of the human metabolism, lipids are also involved in metabolic diseases, cardiovascular and renal diseases, cancer and/or hepatological and neurological ...
William Griffiths, Yuqin Wang
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Evaluation of Normalization Approaches for Quantitative Analysis of Bile Acids in Human Feces
Metabolites, 2022 Quantitative analysis of bile acids in human feces can potentially help to better understand the influence of the gut microbiome and diet on human health.
Hans-Frieder Schött +5 more
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Identification of plasma lipid biomarkers for prostate cancer by lipidomics and bioinformatics [PDF]
, 2012 Background: Lipids have critical functions in cellular energy storage, structure and signaling. Many individual lipid molecules have been associated with the evolution of prostate cancer; however, none of them has been approved to be used as a ...
AA Elgamal +58 more
core +15 more sources
Analytical and Bioanalytical Chemistry, 2018 The state-of-art in the lipidomic analysis is summarized here to provide the overview of available sample preparation strategies, mass spectrometry (MS)-based methods for the qualitative analysis of lipids, and the quantitative MS approaches for high-throughput clinical workflows.
Michal Holčapek +2 more
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Nature Communications, 2023 The circulatory lipidome is a valuable source for disease markers, but reliable marker discovery requires continuous development of lipidomic methods for large-scale clinical profiling.
Raissa Lerner +7 more
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Metabolites, 2021 Cancer metabolism is associated with the enhanced lipogenesis required for rapid growth and proliferation. However, the magnitude of dysregulation of diverse lipid species still requires significant characterization, particularly in ovarian clear cell ...
Sartaj Ahmad Mir +8 more
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Plant Signaling & Behavior, 2011 A wealth of information related to lipid metabolism and signaling has been revealed in recent years using mass spectrometric-based lipidomics methods. Although quantitatively sensitive, these compositional profiling methods rely on conventional tissue extractions of total lipids which results in a loss of original cellular context of lipid metabolites.
Patrick J, Horn, Kent D, Chapman
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Variability of Lipids in Human Milk
Metabolites, 2021 Lipids in breastmilk play a critical role in infant growth and development. However, few studies have investigated sources of variability of both high- and low-abundant milk lipids.
Jayashree Selvalatchmanan +8 more
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