Results 11 to 20 of about 40,787 (289)
Lipidomics unveils the complexity of the lipidome in metabolic diseases [PDF]
Clinical and Translational Medicine, 2018 Dysregulation of lipid metabolism is responsible for pathologies of human diseases including metabolic diseases. Recent advances in lipidomics analysis allow for the targeted and untargeted identification of lipid species and for their quantification in ...
Young-Hwa Goo, Todd Lydic
exaly +5 more sources
Analytical and Bioanalytical Chemistry, 2015 Profiling of the individual lipids in biological fluids is of great concern with respect to human health and disease; as a consequence, the task of lipid analysis and profiling has become ever increasingly important, and lipidomics has become the target of postgenomic research.
DONATO, Paola Agata Eustochia +4 more
core +7 more sources
, 2023 Lipids are historically considered a source of energy and a component of cell membranes. Over the last years, many other functions have been studied, and their importance in our health is well established. For this reason, studies on lipidomics have been increasing in the clinical and food science areas.
Robert C. Murphy, Alfred H. Merrill
core +5 more sources
, 2013 Lipids are a diverse group of compounds with multiple key biological functions. Lipidomics is a subdiscipline of metabolomics, with the focus on the global study of molecular lipids, including pathways and networks of cellular lipids in biological systems.
Pondia Pons Isabel, Hyötyläinen Tuulia
core +4 more sources
Clinica Chimica Acta, 2020 The present article examines recently published literature on lipids, mainly focusing on research involving glycero-, glycerophospho- and sphingo-lipids. The primary aim is identification of distinct profiles in biologic lipidomic systems by ultra-high-performance liquid chromatography (UHPLC) coupled with mass spectrometry (MS, tandem MS) with ...
Henri F. Avela, Heli Sirén
openaire +2 more sources
Evaluation of Normalization Approaches for Quantitative Analysis of Bile Acids in Human Feces
Metabolites, 2022 Quantitative analysis of bile acids in human feces can potentially help to better understand the influence of the gut microbiome and diet on human health.
Hans-Frieder Schött +5 more
doaj +1 more source
Nature Communications, 2023 The circulatory lipidome is a valuable source for disease markers, but reliable marker discovery requires continuous development of lipidomic methods for large-scale clinical profiling.
Raissa Lerner +7 more
doaj +1 more source
Analytical and Bioanalytical Chemistry, 2018 The state-of-art in the lipidomic analysis is summarized here to provide the overview of available sample preparation strategies, mass spectrometry (MS)-based methods for the qualitative analysis of lipids, and the quantitative MS approaches for high-throughput clinical workflows.
Michal Holčapek +2 more
openaire +5 more sources
Metabolites, 2021 Cancer metabolism is associated with the enhanced lipogenesis required for rapid growth and proliferation. However, the magnitude of dysregulation of diverse lipid species still requires significant characterization, particularly in ovarian clear cell ...
Sartaj Ahmad Mir +8 more
doaj +1 more source
A Pipeline for Making 31P NMR Accessible for Small- and Large-Scale Lipidomics Studies [PDF]
, 2021 Detailed molecular analysis is of increasing importance in research into the regulation of biochemical pathways, organismal growth and disease. Lipidomics in particular is increasingly sought after as it provides insight into molecular species involved ...
Albert, Koulman +6 more
core +1 more source