Results 21 to 30 of about 42,745 (295)

Lipidomics [PDF]

Advanced Drug Delivery Reviews, 2020
Lipids are ubiquitous in the human organism and play essential roles as components of cell membranes and hormones, for energy storage or as mediators of cell signaling pathways. As crucial mediators of the human metabolism, lipids are also involved in metabolic diseases, cardiovascular and renal diseases, cancer and/or hepatological and neurological ...
Wu, Zhuojun, Bagarolo, Giulia Ilaria, Thoroee-Boveleth, Sven, Jankowski, Joachim   +3 more
  +4 more sources

A DMS Shotgun Lipidomics Workflow Application to Facilitate High-Throughput, Comprehensive Lipidomics [PDF]

, 2021
Differential mobility spectrometry (DMS) is highly useful for shotgun lipidomic analysis because it overcomes difficulties in measuring isobaric species within a complex lipid sample and allows for acyl tail characterization of phospholipid species ...
Daniel Hornburg, Mackenzie J. Pearson, Daniel Raftery, Kevin J. Williams, Martin Giera, Steven J. Bensinger, Wei-Yuan Hsieh, Daniel Raftery (186766), Michael P. Snyder (179108), Daniel Hornburg (1998733), Lisa F. Bettcher, Wei-Yuan Hsieh (11540369), Michael P. Snyder, Martin Giera (1598620), Niek Blomberg, Mackenzie J. Pearson (11540372), Lisa F. Bettcher (10099320), Niek Blomberg (11011536), Baolong Su (11540366), Steven J. Bensinger (11540375), Baolong Su, Kevin J. Williams (9369847)   +21 more
core   +3 more sources

Using neurolipidomics to identify phospholipid mediators of synaptic (dys)function in Alzheimer’s Disease

Frontiers in Physiology, 2013
Not all of the mysteries of life lie in our genetic code. Some can be found buried in our membranes. These shells of fat, sculpted in the central nervous system into the cellular (and subcellular) boundaries of neurons and glia, are themselves complex ...
Steffany A L Bennett, Steffany A L Bennett, Nicolas eValenzuela, Nicolas eValenzuela, Hongbin eXu, Hongbin eXu, Bettina eFranko, Bettina eFranko, Stephen eFai, Stephen eFai, Daniel eFigeys, Daniel eFigeys   +11 more
doaj   +1 more source

Myocardial Lipidomics. Developments in myocardial nuclear lipidomics [PDF]

Frontiers in Bioscience, 2007
The development of electrospray ionization mass spectrometry has been critical for the analyses of lipidomes from subcellular organelles. The myocardial nuclear lipidome likely has a key role in the molecular regulation of gene expression. In fact, recent studies have suggested that specific phospholipid classes bind and regulate specific transcription
Carolyn J, Albert, Dhanalakshmi S, Anbukumar, Julie K, Monda, Joseph T, Eckelkamp, David A, Ford   +4 more
openaire   +2 more sources

CRISPR/dCas9 Transcriptional Activation of Endogenous Apolipoprotein AI and Paraoxonase 1 in Enterocytes Alleviates Endothelial Cell Dysfunction

Biomolecules, 2021
Atherosclerosis is the main cause of cardiovascular diseases with high prevalence worldwide. A promising therapeutic strategy to reverse atherosclerotic process is to improve the athero-protective potential of high-density lipoproteins (HDL).
Laura Toma, Teodora Barbălată, Gabriela M. Sanda, Loredan S. Niculescu, Anca V. Sima, Camelia S. Stancu   +5 more
doaj   +1 more source

Identification of plasma lipid biomarkers for prostate cancer by lipidomics and bioinformatics [PDF]

, 2012
Background: Lipids have critical functions in cellular energy storage, structure and signaling. Many individual lipid molecules have been associated with the evolution of prostate cancer; however, none of them has been approved to be used as a ...
Xinchun Zhou, Mary R. Roth, Junmei Ai (120198), Mao, Jinghe, Junmei Ai, Steven A Bigler, Youping Deng (4234), Mary R Roth, Bigler, Steven A., Deng, Youping, Ruth Welti (120203), Ai, Junmei, Charles Pound, Ruth Welti, Roth, Mary R., Xinchun Zhou (120195), Jinghe Mao (47643), Jeffrey Henegar, Steven A. Bigler (120204), Jeffrey Henegar (120202), Henegar, Jeffrey, Youping Deng, Pound, Charles, Jinghe Mao, Charles Pound (120201), Welti, Ruth, Mary R. Roth (120200), Steven A. Bigler, Zhou, Xinchun, Pound Charles, Ai Junmei, Henegar Jeffrey, Roth Mary R., Zhou Xinchun, Bigler Steven A., Mao Jinghe, Deng Youping, Welti Ruth   +37 more
core   +2 more sources

Correction: Vu et al. Specific Changes in Arabidopsis thaliana Rosette Lipids during Freezing Can Be Associated with Freezing Tolerance. Metabolites 2022, 12, 385

Metabolites, 2023
There was an error in the original publication [...]
Hieu Sy Vu, Sunitha Shiva, Thilani Samarakoon, Maoyin Li, Sujon Sarowar, Mary R. Roth, Pamela Tamura, Samuel Honey, Kaleb Lowe, Hollie Porras, Neema Prakash, Charles A. Roach, Morgan Stuke, Xuemin Wang, Jyoti Shah, Gary Gadbury, Haiyan Wang, Ruth Welti   +17 more
doaj   +1 more source

An efficient modified method for plant leaf lipid extraction results in improved recovery of phosphatidic acid

Plant Methods, 2018
Background Lipidomics plays an important role in understanding plant adaptation to different stresses and improving our knowledge of the genes underlying lipid metabolism.
Sunitha Shiva, Regina Enninful, Mary R. Roth, Pamela Tamura, Krishna Jagadish, Ruth Welti   +5 more
doaj   +1 more source

Lipidomics data

, 2022
Non-targeted Lipidomics ...
Nan, Y (via Mendeley Data), Nan, Yabing
core   +2 more sources

Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release

Nature Communications, 2023
Microglial reactivity is a pathological hallmark in many neurodegenerative diseases. During stimulation, microglia undergo complex morphological changes, including loss of their characteristic ramified morphology, which is routinely used to detect and ...
Max Adrian, Martin Weber, Ming-Chi Tsai, Caspar Glock, Olga I. Kahn, Lilian Phu, Tommy K. Cheung, William J. Meilandt, Christopher M. Rose, Casper C. Hoogenraad   +9 more
doaj   +1 more source