Results 21 to 30 of about 51,608 (289)

Generation and quality control of lipidomics data for the alzheimers disease neuroimaging initiative cohort. [PDF]

open access: yes, 2018
Alzheimers disease (AD) is a major public health priority with a large socioeconomic burden and complex etiology. The Alzheimer Disease Metabolomics Consortium (ADMC) and the Alzheimer Disease Neuroimaging Initiative (ADNI) aim to gain new biological ...
AA Willette   +42 more
core   +2 more sources

Recent Advances in Lipidomics and Its Application in Food Science [PDF]

open access: yesShipin Kexue, 2023
Lipids, one of the important nutrients in foods, are a complex class of biomolecules, which play key roles in the processing of different biomolecules. Lipids affect the quality, nutrition and hygiene of foods, and are directly related to the occurrence ...
WANG Xinhui, SONG Xuejian, ZHANG Dongjie, LI Zhijiang
doaj   +1 more source

Cross-Platform Comparison of Untargeted and Targeted Lipidomics Approaches on Aging Mouse Plasma. [PDF]

open access: yes, 2018
Lipidomics - the global assessment of lipids - can be performed using a variety of mass spectrometry (MS)-based approaches. However, choosing the optimal approach in terms of lipid coverage, robustness and throughput can be a challenging task.
Brunet, Anne   +6 more
core   +3 more sources

CRISPR/dCas9 Transcriptional Activation of Endogenous Apolipoprotein AI and Paraoxonase 1 in Enterocytes Alleviates Endothelial Cell Dysfunction

open access: yesBiomolecules, 2021
Atherosclerosis is the main cause of cardiovascular diseases with high prevalence worldwide. A promising therapeutic strategy to reverse atherosclerotic process is to improve the athero-protective potential of high-density lipoproteins (HDL).
Laura Toma   +5 more
doaj   +1 more source

Cellular lipidomics [PDF]

open access: yesThe EMBO Journal, 2005
The cellular lipidome comprises over 1000 different lipids. Most lipids look similar having a polar head and hydrophobic tails. Still, cells recognize lipids with exquisite specificity. The functionality of lipids is determined by their local concentration, which varies between organelles, between the two leaflets of the lipid bilayer and even within ...
openaire   +3 more sources

An efficient modified method for plant leaf lipid extraction results in improved recovery of phosphatidic acid

open access: yesPlant Methods, 2018
Background Lipidomics plays an important role in understanding plant adaptation to different stresses and improving our knowledge of the genes underlying lipid metabolism.
Sunitha Shiva   +5 more
doaj   +1 more source

Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release

open access: yesNature Communications, 2023
Microglial reactivity is a pathological hallmark in many neurodegenerative diseases. During stimulation, microglia undergo complex morphological changes, including loss of their characteristic ramified morphology, which is routinely used to detect and ...
Max Adrian   +9 more
doaj   +1 more source

Correction: Vu et al. Specific Changes in Arabidopsis thaliana Rosette Lipids during Freezing Can Be Associated with Freezing Tolerance. Metabolites 2022, 12, 385

open access: yesMetabolites, 2023
There was an error in the original publication [...]
Hieu Sy Vu   +17 more
doaj   +1 more source

Untargeted Lipidomic Analysis to Broadly Characterize the Effects of Pathogenic and Non-Pathogenic Staphylococci on Mammalian Lipids [PDF]

open access: yes, 2018
Modification of the host lipidome via secreted enzymes is an integral, but often overlooked aspect of bacterial pathogenesis. In the current era of prevalent antibiotic resistance, knowledge regarding critical host pathogen lipid interactions has the ...
Baker, Paul RS   +5 more
core   +4 more sources

Neuronal porosome lipidome [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2014
AbstractCup‐shaped lipoprotein structures called porosomes are the universal secretory portals at the cell plasma membrane, where secretory vesicles transiently dock and fuse to release intravesicular contents. In neurons, porosomes measure ~15 nm and are comprised of nearly 40 proteins, among them SNAREs, ion channels, the Gαo G‐protein and several ...
Lewis, Kenneth T   +3 more
openaire   +2 more sources

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