Results 31 to 40 of about 40,787 (289)

Myocardial Lipidomics. Developments in myocardial nuclear lipidomics [PDF]

Frontiers in Bioscience, 2007
The development of electrospray ionization mass spectrometry has been critical for the analyses of lipidomes from subcellular organelles. The myocardial nuclear lipidome likely has a key role in the molecular regulation of gene expression. In fact, recent studies have suggested that specific phospholipid classes bind and regulate specific transcription
Carolyn J, Albert, Dhanalakshmi S, Anbukumar, Julie K, Monda, Joseph T, Eckelkamp, David A, Ford   +4 more
openaire   +2 more sources

CRISPR/dCas9 Transcriptional Activation of Endogenous Apolipoprotein AI and Paraoxonase 1 in Enterocytes Alleviates Endothelial Cell Dysfunction

Biomolecules, 2021
Atherosclerosis is the main cause of cardiovascular diseases with high prevalence worldwide. A promising therapeutic strategy to reverse atherosclerotic process is to improve the athero-protective potential of high-density lipoproteins (HDL).
Laura Toma, Teodora Barbălată, Gabriela M. Sanda, Loredan S. Niculescu, Anca V. Sima, Camelia S. Stancu   +5 more
doaj   +1 more source

Lipidomics in Food Industry and Nutrition

, 2023
Foodomics is the application of advanced omics approaches for the analysis of food composition, food authenticity, and food quality. Among the different approaches, lipidomics, the metabolomics branch that studies lipids within a living system, has been ...
Micalizzi G., Donnarumma D., Mondello L., Dugo P.   +3 more
core   +1 more source

An efficient modified method for plant leaf lipid extraction results in improved recovery of phosphatidic acid

Plant Methods, 2018
Background Lipidomics plays an important role in understanding plant adaptation to different stresses and improving our knowledge of the genes underlying lipid metabolism.
Sunitha Shiva, Regina Enninful, Mary R. Roth, Pamela Tamura, Krishna Jagadish, Ruth Welti   +5 more
doaj   +1 more source

Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release

Nature Communications, 2023
Microglial reactivity is a pathological hallmark in many neurodegenerative diseases. During stimulation, microglia undergo complex morphological changes, including loss of their characteristic ramified morphology, which is routinely used to detect and ...
Max Adrian, Martin Weber, Ming-Chi Tsai, Caspar Glock, Olga I. Kahn, Lilian Phu, Tommy K. Cheung, William J. Meilandt, Christopher M. Rose, Casper C. Hoogenraad   +9 more
doaj   +1 more source

Correction: Vu et al. Specific Changes in Arabidopsis thaliana Rosette Lipids during Freezing Can Be Associated with Freezing Tolerance. Metabolites 2022, 12, 385

Metabolites, 2023
There was an error in the original publication [...]
Hieu Sy Vu, Sunitha Shiva, Thilani Samarakoon, Maoyin Li, Sujon Sarowar, Mary R. Roth, Pamela Tamura, Samuel Honey, Kaleb Lowe, Hollie Porras, Neema Prakash, Charles A. Roach, Morgan Stuke, Xuemin Wang, Jyoti Shah, Gary Gadbury, Haiyan Wang, Ruth Welti   +17 more
doaj   +1 more source

Cellular lipidomics [PDF]

The EMBO Journal, 2005
The cellular lipidome comprises over 1000 different lipids. Most lipids look similar having a polar head and hydrophobic tails. Still, cells recognize lipids with exquisite specificity. The functionality of lipids is determined by their local concentration, which varies between organelles, between the two leaflets of the lipid bilayer and even within ...
openaire   +3 more sources

The impact of genetic stress by ATGL deficiency on the lipidome of lipid droplets from murine hepatocytes

Journal of Lipid Research, 2013
We showed earlier that nutritional stress like starvation or high-fat diet resulted in phenotypic changes in the lipidomes of hepatocyte lipid droplets (LDs), representative for the pathophysiological status of the mouse model.
Chandramohan Chitraju, Martin Trötzmüller, Jürgen Hartler, Heimo Wolinski, Gerhard G. Thallinger, Guenter Haemmerle, Rudolf Zechner, Robert Zimmermann, Harald C. Köfeler, Friedrich Spener   +9 more
doaj   +1 more source

Recent Advances in Lipidomics and Its Application in Food Science [PDF]

Shipin Kexue, 2023
Lipids, one of the important nutrients in foods, are a complex class of biomolecules, which play key roles in the processing of different biomolecules. Lipids affect the quality, nutrition and hygiene of foods, and are directly related to the occurrence ...
WANG Xinhui, SONG Xuejian, ZHANG Dongjie, LI Zhijiang
doaj   +1 more source

Identification of plasma lipid biomarkers for prostate cancer by lipidomics and bioinformatics [PDF]

, 2012
Background: Lipids have critical functions in cellular energy storage, structure and signaling. Many individual lipid molecules have been associated with the evolution of prostate cancer; however, none of them has been approved to be used as a ...
Xinchun Zhou, Mary R. Roth, Junmei Ai (120198), Mao, Jinghe, Junmei Ai, Steven A Bigler, Youping Deng (4234), Mary R Roth, Bigler, Steven A., Deng, Youping, Ruth Welti (120203), Ai, Junmei, Charles Pound, Ruth Welti, Roth, Mary R., Xinchun Zhou (120195), Jinghe Mao (47643), Jeffrey Henegar, Steven A. Bigler (120204), Jeffrey Henegar (120202), Henegar, Jeffrey, Youping Deng, Pound, Charles, Jinghe Mao, Charles Pound (120201), Welti, Ruth, Mary R. Roth (120200), Steven A. Bigler, Zhou, Xinchun   +28 more
core   +2 more sources