Results 41 to 50 of about 36,737 (293)
Regulation of microRNAs in high-fat diet induced hyperlipidemic hamsters
Dyslipidemia is a documented risk factor for cardiovascular diseases and other metabolic disorders. Therefore, the analysis of hyperlipidemia (HL)-related miRNAs is a potential approach for achieving new prognostic markers in lipid-metabolism related ...
Teodora Barbalata +7 more
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While the roles of a few specific lipids in plant freezing tolerance are understood, the effect of many plant lipids remains to be determined. Acclimation of plants to non-freezing cold before exposure to freezing temperatures improves the outcome of ...
Hieu Sy Vu +17 more
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Abstract Lipid metabolism and signalling play pivotal functions in biology and disease development. Despite this, there is currently no optical technique available that can directly visualise the lipidome in tissues. In this study, we introduce opto-lipidomics, a new approach to optical molecular tissue imaging. We expand the capability
Magnus Jensen +13 more
openaire +3 more sources
Advances in mass spectrometry for lipidomics [PDF]
Recent expansion in research in the field of lipidomics has been driven by the development of new mass spectrometric tools and protocols for the identification and quantification of molecular lipids in complex matrices.
Todd W. Mitchell +3 more
core +1 more source
Bioinformatics for Quantitative, Targeted Lipidomics Discovery [PDF]
Lipidomics uses high performance liquid chromatography coupled to tandem mass spectrometry via electrospray ionization to comprehensively identify and quantify all lipid species in a biological system.
Chitpin, Justin Gareth
core +1 more source
Analytical strategies in lipidomics and applications in disease biomarker discovery [PDF]
Lipidomics is a lipid-targeted metabolomics approach aiming at comprehensive analysis of lipids in biological systems. Recently, lipid profiling, or so-called lipidomics research, has captured increased attention due to the well-recognized roles of ...
Greef, J. van der +12 more
core +1 more source
Atherosclerosis is the main process behind cardiovascular diseases (CVD), maladies which continue to be responsible for up to 70% of death worldwide. Despite the ongoing development of new and potent drugs, their incomplete efficacy, partial intolerance ...
Laura Toma +5 more
doaj +1 more source
ABSTRACTLipidomics is a distinct subspecialty of metabolomics concerned with hydrophobic molecules that organize into membranes. Most of the lipid classes present inMycobacterium tuberculosisare found only inActinobacteriaand show extreme structural diversity. This article highlights the conceptual basis and the practical challenges associated with the
Layre, Emilie +3 more
openaire +2 more sources
Understanding the Lipidome at the Systems Level with lipidomeR [PDF]
Abstract Lipidomics is one of the fastest-growing areas of molecular profiling in medicine. While increasing amounts of lipidomics data are generated, tools for analyzing and interpreting these data are not equally widely available. We present the lipidomeR -- a tool specifically designed for systematic interpretation of large lipidome ...
Suvitaival, Tommi +1 more
openaire +1 more source

