Results 11 to 20 of about 72,943 (293)

Differences in levels of phosphatidylinositols in healthy and stable Coronary Artery Disease subjects revealed by HILIC-MRM method with SERRF normalization.

PLoS ONE, 2021
Quantification of endogenous biomarkers in clinical studies requires careful evaluation of a number of assay performance parameters. Comparisons of absolute values from several clinical studies can enable retrospective analyses further elucidating the ...
Yue Huang, Ruipeng Mu, David Wen, Joseph S Grimsby, Meina Liang, Anton I Rosenbaum   +5 more
doaj   +2 more sources

Resolution of intact phosphatidylinositols by argentation thin-layer chromatography

Journal of Lipid Research, 1971
An argentation thin-layer chromatographic method is described for the separation of intact phosphatidylinositols on the basis of the degree of unsaturation of their component fatty acids.
B.J. Holub, A. Kuksis
doaj   +2 more sources

Separation of phosphatidylinositols and other phospholipids by two-step one-dimensional thin-layer chromatography.

Journal of Lipid Research, 1989
A quick and efficient thin-layer chromatographic procedure is described for the separation of phosphatidylinositol-4,5-bisphosphate, phosphatidylinositol-4-monophosphate, phosphatidylinositol, phosphatidylcholine, phosphatidic acid, and ...
J D Medh, P H Weigel
doaj   +2 more sources

Tuberculostearic Acid-Containing Phosphatidylinositols as Markers of Bacterial Burden in Tuberculosis

ACS Infectious Diseases, 2022
One-fourth of the global human population is estimated to be infected with strains of the Mycobacterium tuberculosis complex (MTBC), the causative agent of tuberculosis (TB). Using lipidomic approaches, we show that tuberculostearic acid (TSA)-containing
Julius Brandenburg, J. Heyckendorf, Franziska Marwitz, Nicole Zehethofer, Lara Linnemann, N. Gisch, H. Karaköse, M. Reimann, K. Kranzer, B. Kalsdorf, Patricia M Sánchez-Carballo, Michael Weinkauf, Verena Scholz, S. Malm, S. Homolka, K. Gaede, C. Herzmann, U. Schaible, Christoph Hölscher, N. Reiling, D. Schwudke   +20 more
semanticscholar   +1 more source

Lipidome-Wide Characterization of Phosphatidylinositols and Phosphatidylglycerols on C=C Location Level

Analytica Chimica Acta, 2020
Phosphatidylglycerol (PG) and phosphatidylinositol (PI) are two essential classes of glycerophospholipids (GPs), playing versatile roles such as signalling messengers and lipid-protein interaction ligands in cell.
Tian Xia, Hanlin Ren, Wenpeng Zhang, Yu Xia   +3 more
semanticscholar   +1 more source

Maternal lipidomic signatures in relation to spontaneous preterm birth and large-for-gestational age neonates

Scientific Reports, 2021
Lipidome-wide metabolites may be useful biomarkers of pregnancy outcomes. We sought to characterize maternal lipidomic signatures associated with preterm birth and neonatal anthropometric parameters.
Max T. Aung, Pahriya Ashrap, Deborah J. Watkins, Bhramar Mukherjee, Zaira Rosario, Carmen M. Vélez-Vega, Akram N. Alshawabkeh, José F. Cordero, John D. Meeker   +8 more
doaj   +1 more source

Phosphatidylinositol 4-kinases [PDF]

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1998
Polyphosphoinositides are involved in many signal transduction pathways in eukaryotic cells. The first committed step is catalysed by phosphatidylinositol 4‐kinase leading to the formation of phosphatidylinositol 4‐phosphate. In the last four years, ten cDNA molecules have been cloned which code isoforms of phosphatidylinositol 4‐kinase; some of which ...
T, Gehrmann, L M, Heilmeyer
openaire   +4 more sources

Phosphoinositides signaling modulates microglial actin remodeling and phagocytosis in Alzheimer’s disease

Cell Communication and Signaling, 2021
Alzheimer’s disease is one of the neurodegenerative diseases, characterized by the accumulation of abnormal protein deposits, which disrupts signal transduction in neurons and other glia cells.
Smita Eknath Desale, Subashchandrabose Chinnathambi   +1 more
doaj   +1 more source

Worms, Fat, and Death: Caenorhabditis elegans Lipid Metabolites Regulate Cell Death

Metabolites, 2021
Caenorhabditis elegans is well-known as the model organism used to elucidate the genetic pathways underlying the first described form of regulated cell death, apoptosis. Since then, C.
Marcos A. Perez, Jennifer L. Watts
doaj   +1 more source

Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis

eLife, 2017
Phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] is essential for exocytosis. Classical ways of manipulating PI(4,5)P2 levels are slower than its metabolism, making it difficult to distinguish effects of PI(4,5)P2 from those of its metabolites.
Alexander M Walter, Rainer Müller, Bassam Tawfik, Keimpe DB Wierda, Paulo S Pinheiro, André Nadler, Anthony W McCarthy, Iwona Ziomkiewicz, Martin Kruse, Gregor Reither, Jens Rettig, Martin Lehmann, Volker Haucke, Bertil Hille, Carsten Schultz, Jakob Balslev Sørensen   +15 more
doaj   +1 more source