Results 21 to 30 of about 73,691 (318)
Analytica Chimica Acta, 2020 Phosphatidylglycerol (PG) and phosphatidylinositol (PI) are two essential classes of glycerophospholipids (GPs), playing versatile roles such as signalling messengers and lipid-protein interaction ligands in cell.
Tian Xia +3 more
semanticscholar +1 more source
Regulation of Necroptosis by Phospholipids and Sphingolipids
Cells, 2020 Several non-apoptotic regulated cell death pathways have been recently reported. Necroptosis, a form of necrotic-regulated cell death, is characterized by the involvement of receptor-interacting protein kinases and/or the pore-forming mixed lineage ...
Xuewei Zhang +4 more
doaj +1 more source
Scientific Reports, 2021 Lipidome-wide metabolites may be useful biomarkers of pregnancy outcomes. We sought to characterize maternal lipidomic signatures associated with preterm birth and neonatal anthropometric parameters.
Max T. Aung +8 more
doaj +1 more source
Phosphatidylinositol 4-kinases [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1998 Polyphosphoinositides are involved in many signal transduction pathways in eukaryotic cells. The first committed step is catalysed by phosphatidylinositol 4‐kinase leading to the formation of phosphatidylinositol 4‐phosphate. In the last four years, ten cDNA molecules have been cloned which code isoforms of phosphatidylinositol 4‐kinase; some of which ...
T, Gehrmann, L M, Heilmeyer
openaire +4 more sources
Cell Communication and Signaling, 2021 Alzheimer’s disease is one of the neurodegenerative diseases, characterized by the accumulation of abnormal protein deposits, which disrupts signal transduction in neurons and other glia cells.
Smita Eknath Desale +1 more
doaj +1 more source
Worms, Fat, and Death: Caenorhabditis elegans Lipid Metabolites Regulate Cell Death
Metabolites, 2021 Caenorhabditis elegans is well-known as the model organism used to elucidate the genetic pathways underlying the first described form of regulated cell death, apoptosis. Since then, C.
Marcos A. Perez, Jennifer L. Watts
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Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis
eLife, 2017 Phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] is essential for exocytosis. Classical ways of manipulating PI(4,5)P2 levels are slower than its metabolism, making it difficult to distinguish effects of PI(4,5)P2 from those of its metabolites.
Alexander M Walter +15 more
doaj +1 more source
The ether lipid precursor hexadecylglycerol causes major changes in the lipidome of HEp-2 cells. [PDF]
PLoS ONE, 2013 The ether-lipid precursor sn-1-O-hexadecylglycerol (HG) can be used to compensate for early metabolic defects in ether-lipid biosynthesis. To investigate a possible metabolic link between ether-linked phospholipids and the rest of the cellular lipidome ...
Jonas Bergan +5 more
doaj +1 more source
Function of Phosphatidylinositol in Mycobacteria [PDF]
Journal of Biological Chemistry, 2005 Phosphatidylinositol (PI) is an abundant phospholipid in the cytoplasmic membrane of mycobacteria and the precursor for more complex glycolipids, such as the PI mannosides (PIMs) and lipoarabinomannan (LAM). To investigate whether the large steady-state pools of PI and apolar PIMs are required for mycobacterial growth, we have generated a Mycobacterium
Ruth E, Haites +3 more
openaire +2 more sources
Ion Mobility–Mass Spectrometry Approach for the Comparison of Sheep and Goat Milk Lipidomes
Applied Sciences, 2023 In this work, we report an analytical procedure to investigate the lipid compositions of sheep and goat milk. This approach is based on an ion mobility–high-resolution mass spectrometric method to facilitate the identification of complex lipid species ...
Cristina Manis +5 more
doaj +1 more source