Results 41 to 50 of about 22,548 (354)

Lipid Polarization during Cytokinesis

open access: yesCells, 2022
The plasma membrane of eukaryotic cells is composed of a large number of lipid species that are laterally segregated into functional domains as well as asymmetrically distributed between the outer and inner leaflets.
Govind Kunduri   +2 more
doaj   +1 more source

Lipid changes within the epidermis of living skin equivalents observed across a time-course by MALDI-MS imaging and profiling [PDF]

open access: yes, 2015
© 2015 Mitchell et al. Abstract Background: Mass spectrometry imaging (MSI) is a powerful tool for the study of intact tissue sections. Here, its application to the study of the distribution of lipids in sections of reconstructed living skin equivalents ...
Clench, Malcolm   +4 more
core   +2 more sources

Separation of phosphatidylinositols and other phospholipids by two-step one-dimensional thin-layer chromatography.

open access: yesJournal of Lipid Research, 1989
A quick and efficient thin-layer chromatographic procedure is described for the separation of phosphatidylinositol-4,5-bisphosphate, phosphatidylinositol-4-monophosphate, phosphatidylinositol, phosphatidylcholine, phosphatidic acid, and ...
J D Medh, P H Weigel
doaj   +1 more source

The kinetics of folding of the NSH2 domain from p85 [PDF]

open access: yes, 2019
SH2 domains are protein domains that mediate protein-protein interaction through the recognition and binding of specific sequences containing phosphorylated tyrosines.
Gianni, Stefano   +3 more
core   +2 more sources

The Effect of Polyphenol Extract from Rosa Roxburghii Fruit on Plasma Metabolome and Gut Microbiota in Type 2 Diabetic Mice

open access: yesFoods, 2022
Rosa roxburghii fruit is an underutilized functional food abundant in polyphenols. Polyphenols have been proved to have antidiabetic effects. This study investigates the effects of Rosa roxburghii fruit polyphenols extract (RPE) on plasma metabolites and
Hui Wang   +8 more
doaj   +1 more source

Cross-Platform Comparison of Untargeted and Targeted Lipidomics Approaches on Aging Mouse Plasma. [PDF]

open access: yes, 2018
Lipidomics - the global assessment of lipids - can be performed using a variety of mass spectrometry (MS)-based approaches. However, choosing the optimal approach in terms of lipid coverage, robustness and throughput can be a challenging task.
Brunet, Anne   +6 more
core   +3 more sources

Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2018
Previous work from our group showed that tamoxifen, an oral drug that has been in use for the treatment of breast cancer for over 40 years, is active both in vitro and in vivo against several species of Leishmania, the etiological agent of leishmaniasis.
Cristiana T. Trinconi   +7 more
doaj   +1 more source

Detección de blancos moleculares en la ruta de señalización del fosfatidil-inositol en Leishmania spp. mediante herramientas bioinformáticas y de modelado matemático

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2015
Introducción. La leishmaniasis es una enfermedad de gran impacto en la salud pública. La Organización Mundial de la Salud considera prioritaria la investigación orientada al desarrollo de medicamentos para su tratamiento.
Valeria Velásquez   +2 more
doaj   +1 more source

Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport [PDF]

open access: yes, 1994
. Lipoprotein lipase (LPL) and glycolipidanchored cAMP-binding ectoprotein (Gcel) are modified by glycosyl-phosphatidylinositol (GPI) in rat adipocytes, however, the linkage is potentially unstable. Incubation of the cells with either insulin (0.1-30 nM)
Bandlow, Wolfhard   +3 more
core   +3 more sources

Glycophosphosphingolipid (GSPL) Purification Protocol

open access: yesBio-Protocol, 2012
Glycosylated ceramide phosphorylinositol are present in many species of fungi and mushrooms and bacteria and parasitic organisms like leishmania. These are usually membrane raft associated and are not easily extracted by conventional methodologies.
Tripti De
doaj   +1 more source

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