Results 41 to 50 of about 31,403 (255)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Journal of Lipid Research, 1960 T h e dried crystals melted with decomposition a t about 215”. The substance is probably an organic acid but we have not yet had time to examine it thoroughly.” (1) In this modest way inositol seems to have made its first appearance as a lipid constituent.
openaire +3 more sources
HPLC Separation of Inositol Polyphosphates
, 2010 High performance liquid chromatography (H PLC) is an essential analytical tool in the study of the large number of inositol phosphate isomers. This chapter focuses on the separation of inositol polyphosphates from [H-3]myo-inositol labeled tissues and ...
Barker, Christopher J. +8 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The structure of myo-inositol-hexakisphosphate (InsP6).
, 2018 The structure of myo-inositol-hexakisphosphate (InsP6).
Akira Odani (492835) +3 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Efficient Multi-Enzymes Immobilized on Porous Microspheres for Producing Inositol From Starch
Frontiers in Bioengineering and Biotechnology, 2020 In vitro synthetic enzymatic biosystem is considered to be the next generation of biomanufacturing platform. This biosystem contains multiple enzymes for the implementation of complicated biotransformatiom.
Pingping Han +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
STUDY OF SOME FACTORS AFFECT ON CLONAL PROPAGATION FOR "GARDENIA" PLANT Gardenia jasminoides VAR. VEITCHII BY TISSUE CULTURE [PDF]
Mesopotamia Journal of Agriculture, 2013 This experiments were conducted to study the effect of some important factors on growth and multiplication of ornamental plant dendritic "Gardenia" Gardenia Jasminoides var. Veitchii culturing on MS medium In vitro.
Ammar Zeki Kassab Bashi
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source