Results 31 to 40 of about 13,609,159 (181)

d-Chiro-Inositol in Clinical Practice: A Perspective from the Experts Group on Inositol in Basic and Clinical Research (EGOI).

open access: yesGynecol Obstet Invest
Background: D-chiro-inositol is a natural molecule that, in association with its well-studied isomer myo-inositol, may play a role in treating various metabolic and gynecological disorders. Objectives: This perspective seeks to explore the mechanisms and
Dinicola S   +35 more
europepmc   +2 more sources

d-chiro-Inositol Ribophostin: A Highly Potent Agonist of d-myo-Inositol 1,4,5-Trisphosphate Receptors: Synthesis and Biological Activities

open access: yes, 2020
Analogues of the Ca2+-releasing intracellular messenger d-myo-inositol 1,4,5-trisphosphate [1, Ins­(1,4,5)­P3] are important synthetic targets. Replacement of the α-glucopyranosyl motif in the natural product mimic adenophostin 2 by d-chiro-inositol in d-
Barry V. L. Potter (7526327)   +5 more
core   +2 more sources

PCOS and inositols: controversial results and necessary clarifications. Basic differences between D-chiro and myo-inositol [PDF]

open access: yes, 2021
Myo-Inositol (myo-Ins) and its phosphate derivatives—including inositol phosphates (InsPs), inositol pyrophosphates (IPPs) and phosphatidyl-inositol phosphate (PtdIns)—are credited to act as second messengers, which accumulate rapidly and transiently in ...
Abdel Halim Harrath   +8 more
core   +1 more source

Inositol supplementation - known and possible applications

open access: yesJournal of Education, Health and Sport, 2022
Introduction: Myo-inositol (MYO) and D-chiro-inositol are chemical compounds known to exert an impact on multiple signaling pathways of a human body. Due to its effects on insulin metabolism and ovaries’ hormone activity their use in polycystic ovary ...
Aleksandra Swora   +9 more
doaj   +1 more source

Exogenously applied D-pinitol and D-chiro-inositol modifies the accumulation of α-D-galactosides in developing tiny vetch (Vicia hirsuta [L.] S.F. Gray) seeds

open access: yesActa Societatis Botanicorum Poloniae, 2011
In the present study we have investigated the effect of exogenous cyclitols on the accumulation of their galactosides and raffinose family oligosaccharides (RFOs), as well as on some enzymes important for their biosynthesis in seeds of tiny vetch (Vicia ...
Lesław B. Lahuta   +4 more
doaj   +1 more source

D-chiro-inositol ribophostin: a highly potent agonist at D-myo-inositol 1,4,5-trisphosphate receptors: synthesis and biological activities [PDF]

open access: yes, 2020
Analogues of the Ca2+-releasing intracellular messenger D-myo-inositol 1,4,5-trisphosphate [1, Ins(1,4,5)P3] are important synthetic targets. Replacement of the α-glucopyranosyl motif in the natural product mimic adenophostin 2 by D-chiro-inositol in D ...
Konieczny, Vera   +5 more
core   +1 more source

Effect of D-chiro-inositol on hormonal parameters and insulin resistance in women with polycystic ovary syndrome [PDF]

open access: yes, 2023
Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder among women of reproductive age, characterized by hormonal imbalance and insulin resistance.
Yasmin, Mahamuda   +4 more
core   +1 more source

The Impact of Phytases on the Release of Bioactive Inositols, the Profile of Inositol Phosphates, and the Release of Selected Minerals in the Technology of Buckwheat Beer Production

open access: yesBiomolecules, 2020
A relatively high concentration of phytate in buckwheat malt, and the low activity of endogenous buckwheat phytases, both of which limit the effective use of substrates (starch, proteins, minerals) for fermentation and yeast metabolism, gives rise to the
Robert Duliński   +4 more
doaj   +1 more source

D-chiro-inositol increases antioxidant capacity and longevity of Caenorhabditis elegans via activating Nrf-2/SKN-1 and FOXO/DAF-16

open access: yesExperimental Gerontology, 2023
D-chiro-inositol (DCI) is an isomer of inositol, abundant in many foods, such as beans and buckwheat, with insulin-sensitizing, anti-inflammatory, and antioxidant effects.
Lin Shi   +4 more
doaj   +1 more source

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