Results 31 to 40 of about 2,965 (199)

Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women with PCOS: a network meta-analysis

Reproductive Health, 2021
Plain English summary This study aimed to compare the effects of oral insulin sensitizers on endocrine and metabolic profiles in women with polycystic ovary syndrome (PCOS). A random-effects network meta-analysis including 22 trials was conducted.
Han Zhao, Chuan Xing, Jiaqi Zhang, Bing He   +3 more
doaj   +1 more source

Characterization of new polyol/H+ symporters in Debaryomyces hansenii. [PDF]

PLoS ONE, 2014
Debaryomyces hansenii is a halotolerant yeast that produces and assimilates a wide variety of polyols. In this work we evaluate polyol transport in D. hansenii CBS 767, detecting the occurrence of polyol/H(+) (and sugar/H(+)) symporter activity, through ...
Iliana Pereira, Ana Madeira, Catarina Prista, Maria C Loureiro-Dias, Maria José Leandro   +4 more
doaj   +1 more source

D-chiro-inositol metabolism in diabetes mellitus. [PDF]

Proceedings of the National Academy of Sciences, 1993
D-chiro-inositol is a rare inositol isomer present in inositol phosphoglycans which are proposed mediators of insulin action. To study D-chiro-inositol metabolism in diabetes mellitus, a sensitive and specific assay was developed using negative-ion chemical ionization gas chromatography/mass spectrometry.
R E, Ostlund, J B, McGill, I, Herskowitz, D M, Kipnis, J V, Santiago, W R, Sherman   +5 more
openaire   +2 more sources

Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome [PDF]

, 1999
BACKGROUND Women with the polycystic ovary syndrome have insulin resistance and hyperinsulinemia, possibly because of a deficiency of a d-chiro-inositol–containing phosphoglycan that mediates the action of insulin. We hypothesized that the administration
Allan, Geoffrey, , Ph. D., Gunn, Ronald D., , M.S., Jakubowicz, Daniela J., , M.D., Nestler, John E., Reamer, Paula, , M.A.   +4 more
core   +2 more sources

From Myo-inositol to D-chiro-inositol molecular pathways.

European review for medical and pharmacological sciences, 2021
Inositol is a carbocyclic sugar polyalcohol. By epimerization of its hydroxyl groups, nine possible stereoisomers can be generated, two of major physiological and clinical relevance: myo-inositol and D-chiro-inositol. Myo-inositol and D-chiro-inositol are normally stored in kidney, brain and liver and are necessary for functions, such as signal ...
KIANI A. K., PAOLACCI S., CALOGERO A. E., CANNARELLA R., DI RENZO G. C., GERLI S., DELLA MORTE C., BUSETTO G. M., DE BERARDINIS E., DEL GIUDICE F., STUPPIA L., FACCHINETTI F., DINICOLA S., BERTELLI M.   +13 more
openaire   +3 more sources

Exogenously Applied Cyclitols and Biosynthesized Silver Nanoparticles Affect the Soluble Carbohydrate Profiles of Wheat (Triticum aestivum L.) Seedling

Plants, 2023
Cyclitols, such as myo-inositol and its isomers and methyl derivatives (i.e., d-chiro-inositol and d-pinitol (3-O-methyl-chiro-inositol)), are classified as osmolytes and osmoprotectants and are significantly involved in plant responses to abiotic ...
Lesław B. Lahuta, Joanna Szablińska-Piernik, Karolina Stałanowska, Marcin Horbowicz, Ryszard J. Górecki, Viorica Railean, Paweł Pomastowski, Bogusław Buszewski   +7 more
doaj   +1 more source

D-Chiro-Inositol Improves Sperm Mitochondrial Membrane Potential: In Vitro Evidence. [PDF]

J Clin Med, 2020
The use of inositols in endocrinological clinical practice is increasingly widespread. Most of the existing evidence concerns myoinositol (MYO), the most abundant form in nature, especially in women with polycystic ovarian syndrome. We have previously shown that MYO increases sperm motility in patients with asthenozoospermia by the increase of sperm ...
Condorelli RA, Barbagallo F, Calogero AE, Cannarella R, Crafa A, La Vignera S.   +5 more
europepmc   +4 more sources

Inositol supplementation - known and possible applications

Journal of Education, Health and Sport, 2022
Introduction: Myo-inositol (MYO) and D-chiro-inositol are chemical compounds known to exert an impact on multiple signaling pathways of a human body. Due to its effects on insulin metabolism and ovaries’ hormone activity their use in polycystic ovary ...
Aleksandra Swora, Joanna Borowik, Wojciech Brodowski, Oliwer Sygacz, Piotr Pawłowski, Przemysław Żelazny, Joanna Filipczak, Sara Dankiewicz, Sebastian Bróż, Katarzyna Basta-Arciszewska   +9 more
doaj   +1 more source

Inositol for the prevention of gestational diabetes: a systematic review and meta-analysis of randomized controlled trials [PDF]

, 2018
PURPOSE: Inositol (ISL) embraces a family of simple carbohydrates with insulin-sensitizing properties, whose most common isoforms are Myo-inositol (MYO) and D-chiro inositol (DCI).
Ambrosini, Guido, Berghella, Vincenzo, Cosmi, Erich, Dessole, Francesco, Saccone, Gabriele, Visentin, Silvia, Vitagliano, Amerigo   +6 more
core   +1 more source

A comparative study of combination of Myo-inositol and D-chiro-inositol versus Metformin in the management of polycystic ovary syndrome in obese women with infertility [PDF]

, 2019
Background: Polycystic ovary syndrome (PCOS) is a symptom complex associated with increased amounts of circulating androgens in females, increased insulin resistance and obesity.
Thalamati, Sujana
core   +2 more sources