Results 31 to 40 of about 28,872 (211)

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li, Zhi‐Xian Ye, Xuan‐Yu Chen, Liang‐Liang Qiu, Zhi‐li Chen, Yu‐Sen Qiu, Wei Lin, Ru‐Ying Yuan, Xin‐Tong Yu, Chun‐Yu Huang, Xin‐Yuan Chen, Min‐Ting Lin, Jian‐Ping Hu, Wan‐Jin Chen, Ning Wang, Shao‐Bo Yao, Shi‐Rui Gan, Ying Fu   +17 more
wiley   +1 more source

Myo-Inositol: Pharmacokinetics, Biological Functions, and Therapeutic Potential in Liver Protection: Insights from Preclinical Models. [PDF]

Antioxidants (Basel)
Myo-inositol, the most common stereoisomer of inositol, plays an important role in many physiological processes, such as cell signaling, regulation of glucose and lipid metabolism, and protection of cells against oxidative stress. The main focus has been
Antonowski T, Osowski A, Wojtkiewicz J.
europepmc   +2 more sources

Stereometric Molecular Engineering for Ultra‐Stable Aqueous Zinc‐Ion Batteries

Advanced Functional Materials, EarlyView.
Stereochemical configuration of molecular additives greatly influences interfacial adsorption at the Zn surface. The optimal tilted dual‐anchored adsorption geometry of myo‐inositol constructs a water‐deficient interface and regulates the solvation structure.
Cunxin Liu, Peng Yang, Mohamed H. Helal, Jiang Zhou, Eero Kontturi   +4 more
wiley   +1 more source

In vitro growth of Dendrobium orchid on different concentrations of sucrose and myo-inositol

AGROMIX
Introduction: The limitation of endosperm in seeds requires the propagation of Dendrobium orchid plants to be carried out using in vitro culture techniques.
Hanif Fatur Rohman, Fadil Rohman, Refa Firgiyanto, Riani Ningsih   +3 more
doaj   +1 more source

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

Exogenous myo-inositol alleviates abiotic stress in rapeseed by modulating ion homeostasis and antioxidant defense

Oil Crop Science
Soil salinization is a major abiotic stress that severely constrains global agricultural productivity. The application of exogenous bioactive substances represents a promising strategy to enhance crop salt tolerance.
Shihang Fan, Xulong Zhao, Nian Liu, Xiang Ji, Zihong Huang, Wei Hua, Zhengwei Fu   +6 more
doaj   +1 more source

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

Advanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl, David Holubek, Klaus Speck, Raphael Wildermuth, Franz‐Lucas Haut, Stephan Permann, Immanuel Plangger, Christian Steinborn, Zhigang Rao, Danilo D'Avino, Ida Cerqua, Julia Stadler, Fiorentina Roviezzo, Peter Schlenke, Anita Siller, Harald Schennach, Solveigh C. Koeberle, Eva‐Maria Pferschy‐Wenzig, Antonietta Rossi, Thomas Magauer, Andreas Koeberle   +20 more
wiley   +1 more source

The role of the myo-inositol for the prevention of the gestational diabetes mellitus: systematic review. [PDF]

Rev Bras Ginecol Obstet
Objective: This review evaluated myo-inositol supplementation's effectiveness in pregnant women at high risk for Gestational Diabetes Mellitus (GDM). Sources: A systematic search in PubMed/MedLine, Cochrane, and VHL databases was conducted using the ...
de Holanda TT, Vasconcelos JA, Oliveira NMV, Moreira JLC, Bruno SKB, de Sousa MDRP, Vasconcelos CTM.   +6 more
europepmc   +3 more sources

Dual Repression by IPA1 Fine‐Tunes OsbZIP79‐Mediated Salt Tolerance in Rice

Advanced Science, EarlyView.
Dual repression by IPA1 fine‐tunes OsbZIP79‐mediated salt tolerance in rice: direct transcriptional inhibition under normal conditions and salt‐induced degradation under stress. This dual mechanism activates OsbZIP79 to regulate Na+/K+ homeostasis and redox balance via downstream genes, enabling optimal salt stress response.
Hui Wang, Bo Liu, Can Hu, Chenfan Zheng, Yuting Wei, Xier Xu, Wei Yang, Yu Fang, Guangle Shen, Pedro García‐Caparros, Conghe Zhang, Qingyao Shu, Meng Jiang   +12 more
wiley   +1 more source

Regulatory Effects of Myo-Inositol on Carbohydrate Metabolism and Low-Salinity Adaptation in Pacific White Shrimp (Penaeus vannamei)

Aquaculture Nutrition
This study investigated how dietary myo-inositol affects osmoregulation, carbohydrate and lipid metabolism, immunity, and antioxidant properties in Penaeus vannamei under long-term low-salinity conditions.
Shengwei Lin, Fenglu Han, Zhao Li, Tong Chang, Zelong Zhang, Xianming Xiao, Yiting Wu, Chang Xu, Erchao Li   +8 more
doaj   +1 more source