Results 21 to 30 of about 62,541 (232)

Diabetes, hyperinsulinemia, and hyperlipidemia in small aboriginal community in northern Australia [PDF]

open access: yes, 1990
A small rural Aboriginal community in northern Australia was surveyed for diabetes, impaired glucose tolerance (IGT), hyperinsulinemia, and lipid levels.
Rae, Cheryl   +5 more
core   +1 more source

Suppression of hyperinsulinemia restores growth hormone secretion and metabolism in obese mice

open access: yes, 2021
The well-balanced secretion between insulin and growth hormone (GH) is essential in regulating substrate metabolism, energy metabolism, and body composition.
Veldhuis, JD   +13 more
core   +1 more source

MicroRNAs as Indicators of Malignancy in Pancreatic Ductal Adenocarcinoma (PDAC) and Cystic Pancreatic Lesions

open access: yesCells, 2022
The dysregulation of microRNAs has recently been associated with cancer development and progression in pancreatic ductal adenocarcinoma (PDAC) and cystic pancreatic lesions.
Christian Prinz   +2 more
doaj   +1 more source

High Prevalence of Insulin Resistance in Asymptomatic Patients with Acute Intermittent Porphyria and Liver-Targeted Insulin as a Novel Therapeutic Approach

open access: yesBiomedicines, 2021
Acute porphyria attacks are associated with the strong up-regulation of hepatic heme synthesis and over-production of neurotoxic heme precursors. First-line therapy is based on carbohydrate loading.
Isabel Solares   +11 more
doaj   +1 more source

Hypoglycemia and Hyperinsulinemia in Rodent Models of Severe Malaria Infection [PDF]

open access: yes, 1994
Severe hypoglycemia developed during nonlethal Plasmodium chabaudi and lethal P. yoelii blood stage malaria infection in mice, always in association with hyperinsulinemia. Supernatants of lethal P.
Playfair, J. H. L., Elased, Khalid M.
core   +1 more source

In vitro characterization of the effects of chronic insulin stimulation in mouse 3T3-L1 and human SGBS adipocytes

open access: yesAdipocyte, 2020
Hyperinsulinemia is the hallmark of the development of insulin resistance and precedes the diagnosis of type 2 diabetes. Here we evaluated the effects of prolonged exposure (≥4 days) to high insulin doses (150 nM) in vitro in two adipose cell types ...
A. Rossi   +7 more
doaj   +1 more source

Errata: Hyperinsulinemia: A unifying theory of chronic disease? [PDF]

open access: yes, 2015
Errata: The original article was published with an error of hyperinsulinemia improves fibrinolysis, instead hyperinsulinemia impairs fibrinolysis.
Crofts, Catherine
core   +1 more source

Understanding the Mechanisms of Hyperinsulinemia

open access: yes, 2020
This thesis explored the mechanisms that underlie hyperinsulinemia, or elevated insulin levels, in young adults. It found hyperinsulinemia was associated with increased insulin secretion, decreased insulin clearance, and abnormalities with cellular ...
Steven Douglas Hamley (15334522)
core   +1 more source

Does Oxidative Stress Cause Insulin Resistance in Women with Polycystic Ovary Syndrome?

open access: yesمجله دانشکده پزشکی اصفهان, 2020
Background: Polycystic ovary syndrome (PCOS), with a prevalence of 4-12 percent, is the most common endocrine-metabolic disorder in reproductive age of women.
Farideh Zafari-Zangeneh
doaj   +1 more source

Role of lipotoxicity in achieving glycemic control in patients with diabetes type 2 and obesity

open access: yesМедицинский совет, 2013
Obesity increases the risk of diabetes mellitus type 2 due to the development of insulin resistance. Therapy for diabetes mellitus type 2 is limited by a relatively small amount of knowledge on the mechanisms of insulin resistance, despite the ...
А. S. Ametov   +4 more
doaj   +1 more source

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