Mechanisms linking glucotoxicity to the development of insulin resistance: a role for the endoplasmic reticulum stress [PDF]
Aims/hypothesis: Glucosamine, generated during hyperglycaemia, causes insulin resistance in different cells. Here we sought to evaluate the possible role of ER stress in the induction of insulin-resistance by glucosamine in skeletal muscle cells. Methods:
Iadicicco, Claudia
core +1 more source
Post-operative insulin resistance
Post-operative insulin resistance (IR) is a recognised marker of surgical stress. However, the reasons underlying post-operative IR and its clinical value are still unclear.
Irina Aleksandrovna Tarasova +2 more
doaj +1 more source
Introduction Insulin resistance is becoming an increasingly widespread problem worldwide. For its determination indirect indices of insulin resistance or insulin sensitivity have used. Those indices based on simultaneous measurements of blood glucose and
Sylwia Płaczkowska +3 more
doaj +1 more source
Analysis of factors associated with insulin resistance in young women: A cross-sectional study
Summary: Background & aims: Impaired glucose tolerance in young women may lead to the future development of gestational diabetes mellitus and/or type 2 diabetes mellitus.
Isaki Hanamura +6 more
doaj +1 more source
Role of Myotonic Dystrophy Protein Kinase [DMPK] in Glucose Homeostasis and Muscle Insulin Action [PDF]
Myotonic dystrophy 1 (DM1) is caused by a CTG expansion in the 3′-unstranslated region of the DMPK gene, which encodes a serine/threonine protein kinase. One of the common clinical features of DM1 patients is insulin resistance, which has been associated
Liesa Marc +49 more
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Effect of the dietary fat quality on insulin sensitivity. [PDF]
Recent evidence shows that specific fatty acids affect cell metabolism, modifying the balance between fatty acid oxidation and lipogenesis. These effects may have important implications in addressing the present epidemic of nutrition-related chronic ...
Aguirre, Carolina A +7 more
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Quantifying the improvement of surrogate indices of hepatic insulin resistance using complex measurement techniques [PDF]
We evaluated the ability of simple and complex surrogate-indices to identify individuals from an overweight/obese cohort with hepatic insulin-resistance (HEP-IR).
Martin Osterhoff +35 more
core +2 more sources
Insulin Signaling and Insulin Resistance [PDF]
Insulin resistance or its sequelae may be the common etiology of maladies associated with metabolic syndrome (eg, hypertension, type 2 diabetes, atherosclerosis, heart attack, stroke, and kidney failure). It is thus important to understand those factors that affect insulin sensitivity.
openaire +2 more sources
Insulin Resistance and Hypertension [PDF]
The association between insulin resistance and insulinemia and hypertension is controversial. We examined the relation between insulin resistance and hypertension in 564 non-Hispanic whites (NHW), 505 Hispanics (H), and 413 African Americans (AA) who participated in the Insulin Resistance Atherosclerosis Study (IRAS).
Mohammed F, Saad +9 more
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Insulin resistance in Chileans of European and indigenous descent: evidence for an ethnicity x environment interaction [PDF]
<p><b>Background:</b> Effects of urbanisation on diabetes risk appear to be greater in indigenous populations worldwide than in populations of European origin, but the reasons are unclear.
Jason M R Gill +29 more
core +1 more source

