Novel Therapy in the Management of Insulin Resistance [PDF]
Insulin resistance is a growing phenomenon currently due to the increasing risk factors in modern society. Therefore, treatment of insulin resistance should be of great importance to decrease morbidity and mortality.
Wu, Pei-Ju
core
Analysis of factors associated with insulin resistance in young women: A cross-sectional study
Summary: Background & aims: Impaired glucose tolerance in young women may lead to the future development of gestational diabetes mellitus and/or type 2 diabetes mellitus.
Isaki Hanamura +6 more
doaj +1 more source
Insulin resistance in Chileans of European and indigenous descent: evidence for an ethnicity x environment interaction [PDF]
<p><b>Background:</b> Effects of urbanisation on diabetes risk appear to be greater in indigenous populations worldwide than in populations of European origin, but the reasons are unclear.
Jason M R Gill +29 more
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Hypothesis: ‘Vasocrine’ signalling from perivascular fat - a mechanism linking insulin resistance and vascular disease [PDF]
Adipose tissue expresses cytokines which inhibit insulin signalling pathways in liver and muscle. Obesity also results in impairment of endothelium-dependent vasodilatation to insulin. We propose a vasoregulatory role for local deposits of fat around the
Stehouwer, C.D.A. +7 more
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Insulin resistance in cardiovascular disease, uremia, and peritoneal dialysis. [PDF]
Diabetic nephropathy is highly correlated with the occurrence of other complications of type 1 diabetes (T1D) and type 2 diabetes (T2D) mellitus; for example, hypertension with cardiovascular disease (CVD) being the most frequent cause of death in ...
Davies, Lambie
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Effect of the dietary fat quality on insulin sensitivity. [PDF]
Recent evidence shows that specific fatty acids affect cell metabolism, modifying the balance between fatty acid oxidation and lipogenesis. These effects may have important implications in addressing the present epidemic of nutrition-related chronic ...
Aguirre, Carolina A +7 more
core +1 more source
Quantifying the improvement of surrogate indices of hepatic insulin resistance using complex measurement techniques [PDF]
We evaluated the ability of simple and complex surrogate-indices to identify individuals from an overweight/obese cohort with hepatic insulin-resistance (HEP-IR).
Martin Osterhoff +35 more
core +1 more source
Insulin resistance in morbid obesity: Reversal with intramyocellular fat depletion [PDF]
Obesity is a frequent cause of insulin resistance and poses a major risk for diabetes. Abnormal fat deposition within skeletal muscle has been identified as a mechanism of obesity-associated insulin resistance. We tested the hypothesis that dietary lipid
CAMASTRA S +23 more
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Role of Insulin Resistance in Non-Obese Adolescents [PDF]
2010-08Insulin resistance in the obese is closely related with cardiovascular diseases and their risk factors not only in adults but also in children and adolescents.
Koketsu, Masaaki +4 more
core +1 more source
Role of Myotonic Dystrophy Protein Kinase [DMPK] in Glucose Homeostasis and Muscle Insulin Action [PDF]
Myotonic dystrophy 1 (DM1) is caused by a CTG expansion in the 3′-unstranslated region of the DMPK gene, which encodes a serine/threonine protein kinase. One of the common clinical features of DM1 patients is insulin resistance, which has been associated
Liesa Marc +49 more
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