Results 111 to 120 of about 18,511 (201)

When Acarbose Overdose Turns Severe: Managing Hypoglycemia in an Uncommon Scenario

Clinical Case Reports
Acarbose is usually safe, but overdose can trigger severe, life‐threatening hypoglycemia. In cases of unexplained low blood sugar—particularly in patients with psychiatric illness or access to hypoglycemic drugs—acarbose toxicity should be considered ...
Aron Shrestha, Navin Poudel, Kshitiz Acharya, Arjun Chaudhary, Manish Acharya, Santosh Bastola, Bibek Ghimire   +6 more
doaj   +1 more source

Intervention effect of individualized diet nursing combined with acarbose on blood glucose and intestinal flora of patients with type 2 diabetes

Huli yanjiu, 2016
Objective: To probe into the change situation of blood glucose and intestinal flora of T2DM patients who received the treatment of individualized diet nursing combined with acarbose.Methods:A total of 296 T2DM patients who received and cured from ...
沈婷, 陶琼, 王婧, 陈红, 李玲, 何旭梅, 胡波   +6 more
doaj  

Unraveling the Synergistic Inhibition of Human Maltase-Glucoamylase by Baicalein and Acarbose: Integrated Pharmacodynamics and Computational Insights. [PDF]

Pharmaceuticals (Basel)
He X, Li X, Zhang D, Jiang H, Dong Y.
europepmc   +1 more source

Integrated in Silico and in Vitro Bioactivity Profiling of Selected South African Plant Constituents Against Carbohydrate-Metabolizing Enzymes for Type 2 Diabetes Therapy. [PDF]

Bioinform Biol Insights
Adedirin O, Sabiu S.
europepmc   +1 more source

Novel diazene-tri(phenoxy-1,2,3-triazole-acetamide) derivatives as potent α-glucosidase inhibitors: synthesis, biological evaluation, and <i>in silico</i> studies. [PDF]

RSC Adv
Kermaninia S, Sayahi MH, Halimi M, Mirjalili SZ, Mohammadi H, Abbasi AA, Mojtabavi S, Sepehri N, Hamedifar H, Larijani B, Mohammadi-Khanaposhtani M, Mahdavi M.   +11 more
europepmc   +1 more source

Antidiabetic potential of a novel hydroxyphenyl-bi-benzopyran-hexol compound from Cassia fistula as an α-amylase inhibitor: Integrated in silico screening and in vitro validation using a nonlinear regression model. [PDF]

J Ayurveda Integr Med
Baskar R, Harini M, Selvapriya SS, Hemadevi T, Rajalakshmi A, Kavitha K, Puvanakrishnan R, Ramesh B.   +7 more
europepmc   +1 more source

Utilizing Acarbose as a Model for Pompe Disease

Pompe Disease is a rare autosomal recessive disorder caused by mutations in the alpha-glucosidase (GAA) gene. These mutations leads to a pathological accumulation of glycogen in the lysosome, thereby impairing lysosomal function. At present, most studies
Humadi, Dania, Alvarnaz, Lydia, Sterling, Felicity   +2 more
core   +1 more source

Exploring the α-Glucosidase Inhibitory Activity of Bioactive Compounds from <i>Persicaria odorata</i> (Lour.) Extracts via Integrated In Vitro and In Silico Studies. [PDF]

Int J Mol Sci
Subhan M, Sanachai K, Nutho B, Ratha J, Siriparu P, Datham S, Bangthong B, Padumanonda T, Sungthong B, Puthongking P.   +9 more
europepmc   +1 more source

Cyclitols and Aminocyclitols as Signals: Their Roles in Supporting Ecosystems and Promoting Human Health. [PDF]

J Nat Prod
Skala L, Murdach PK, Hennelly T, Mahmud T.   +3 more
europepmc   +1 more source

Flavonoids and chalcones as selective α-glucosidase inhibitors: from enzymatic screening to validation using the human enzyme. [PDF]

RSC Med Chem
Vicente B, Amaro F, Guedes de Pinho P, Proença C, Corvo ML, Fernandes E, Freitas M.   +6 more
europepmc   +1 more source