Results 111 to 120 of about 2,166,464 (300)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

The accelerated acceleration of the universe

Journal of Cosmology and Astroparticle Physics, 2006
We present a simple mechanism which can mimic dark energy with an equation of state w < -1 as deduced from the supernova data. We imagine that the universe is accelerating under the control of a quintessence field, which is moving up a very gently sloping potential.
Csaki, Csaba, Kaloper, Nemanja, Terning, John   +2 more
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Accelerated Epithelium-Off Corneal Collagen Cross-Linking For Keratoconus: 12-Month Results

Clinical Ophthalmology, 2019
Ismail Ahmed Nagib Omar, Hosny Ahmed Zein Ophthalmology Department, Faculty of Medicine, Minia University, El-Minya, EgyptCorrespondence: Ismail Ahmed Nagib OmarOphthalmology Department, Faculty of Medicine, Minia University, P O Box 61519, El-Minya ...
Omar IAN, Zein HA
doaj  

A qualitative exploration of community knowledge, attitudes, and practices towards tuberculosis in the Karamoja subregion, northeastern Uganda

BMC Health Services Research
Background The Karamoja subregion is a high TB burden pastoralist community that previously had limited access to public health services. We explored the community’s perceptions towards TB to better understand how healthcare services should be structured
William Kasozi, Stella Zawedde-Muyanja, Joseph Musaazi, Alfred Etwom, James Lemukol, Patrick Sagaki, Salome Tino, Cerino Achar, Mary G. Nabukenya-Mudiope, Turyahabwe Stavia, Miriam Murungi, Edmund Rutta, Tadeo Nsubuga, Brenda Picho   +13 more
doaj   +1 more source

Does Fatigue Alter Pitching Mechanics?

Orthopaedic Journal of Sports Medicine, 2016
Objectives: Background: Injuries of the adolescent shoulder and elbow are common in baseball pitchers. Fatigue has been demonstrated to be a risk factor for injury.
Peter Nissen Chalmers MD, Brandon J. Erickson, Terrance Sgroi DPT, Peter Vignona, Matthew Lesniak DPT, Charles A. Bush-Joseph MD, Nikhil N. Verma MD, Anthony A. Romeo MD   +7 more
doaj   +1 more source

An Accelerated Chow and Liu Algorithm: Fitting Tree Distributions to High Dimensional Sparse Data [PDF]

, 1999
Chow and Liu introduced an algorithm for fitting a multivariate distribution with a tree (i.e. a density model that assumes that there are only pairwise dependencies between variables) and that the graph of these dependencies is a spanning tree.
An Accelerated Chow, Liu Algorithm, Marina Meila   +2 more
core   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Postsecondary Pathways Out of Poverty: City University of New York Accelerated Study in Associate Programs and the Case for National Policy

RSF: The Russell Sage Foundation Journal of the Social Sciences, 2018
A postsecondary education holds the promise of higher lifetime earnings and social mobility, but too many low-income students never complete their degrees.
Diana Strumbos, Donna Linderman, Carson C. Hicks   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source