Results 91 to 100 of about 1,985,761 (312)
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Accelerated Epithelium-Off Corneal Collagen Cross-Linking For Keratoconus: 12-Month Results
Clinical Ophthalmology, 2019 Ismail Ahmed Nagib Omar, Hosny Ahmed Zein Ophthalmology Department, Faculty of Medicine, Minia University, El-Minya, EgyptCorrespondence: Ismail Ahmed Nagib OmarOphthalmology Department, Faculty of Medicine, Minia University, P O Box 61519, El-Minya ...
Omar IAN, Zein HA
doaj
Accelerated Adaptive Second Order Super-Twisting Sliding Mode Observer
IEEE Access, 2019 An accelerated second-order super-twisting sliding mode observer with an adaptive gain is proposed for a typical nonlinear system. The key contribution of this algorithm is that the rate of convergence of observation error is accelerated remarkably by ...
Cheng Lin +3 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Accelerated global glacier mass loss in the early twenty-first century
Nature, 2021 R. Hugonnet +10 more
semanticscholar +1 more source
SSRN Electronic JournalWe develop a tractable sticky price model in which the fraction of price changesevolves endogenously over time and, consistent with the evidence, increases with inflation. Because we assume that firms sell multiple products and choose how many, but not which, prices to adjust in any given period, our model admits exact aggregation and reduces to a one ...
Blanco, Andrés +3 more
openaire +2 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Frontiers in PsychiatryTreatment-resistant depression (TRD) poses a significant challenge in psychiatric practice. While repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising non-invasive neuromodulation technique for TRD, a subset of patients fails to
Guilan Sun +3 more
doaj +1 more source
Redox Biology, 2018 Oxidative stress and inflammation interact in the development of diabetic atherosclerosis. Intracellular hyperglycemia promotes production of mitochondrial reactive oxygen species (ROS), increased formation of intracellular advanced glycation end ...
T. Yuan +9 more
semanticscholar +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source