Results 61 to 70 of about 628,696 (290)

Demographic translation and tempo effects: An accelerated failure time perspective

open access: yesDemographic Research, 2006
In this paper I review the concept of tempo effects in demography, focusing on the tempo adjustments proposed by Bongaarts and Feeney and drawing on the work of Ryder and Zeng and Land.
Germán Rodriguez
doaj  

COMPARISON OF SURVIVAL ANALYSIS USING ACCELERATED FAILURE TIME MODEL AND COX MODEL FOR RECIDIVIST CASE

open access: yesBarekeng
Recidivists, or ex-prisoners who commit crimes after serving a prior sentence, pose a critical challenge to the criminal justice system. This study examines social and economic factors that may reduce the likelihood of recidivists being re-arrested ...
Nuraziza Arfan   +3 more
doaj   +1 more source

Mediation Analysis with Survival Outcomes: Accelerated Failure Time Versus Proportional Hazards Models

open access: yesFrontiers in Psychology, 2016
Objective: Survival time is an important type of outcome variable in treatment research. Currently, limited guidance is available regarding performing mediation analyses with survival outcomes, which generally do not have normally distributed errors, and
Lois A Gelfand   +3 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Kernel based methods for accelerated failure time model with ultra-high dimensional data

open access: yesBMC Bioinformatics, 2010
Background Most genomic data have ultra-high dimensions with more than 10,000 genes (probes). Regularization methods with L1 and Lp penalty have been extensively studied in survival analysis with high-dimensional genomic data.
Jiang Feng   +4 more
doaj   +1 more source

Evaluation of the reliability of commercial concentrator triple-junction solar cells by means of accelerated life tests (ALT) [PDF]

open access: yes, 2013
A temperature accelerated life test on commercial concentrator lattice-matched GaInP/GaInAs/Ge triple-junction solar cells has been carried out. The solar cells have been tested at three different temperatures: 119, 126 and 164 °C and the nominal photo ...
Algora del Valle, Carlos   +6 more
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Realistic time-scale fully atomistic simulations of surface nucleation of dislocations in pristine nanopillars [PDF]

open access: yes, 2012
We use our recently proposed accelerated dynamics algorithm (Tiwary and van de Walle, 2011) to calculate temperature and stress dependence of activation free energy for surface nucleation of dislocations in pristine Gold nanopillars under realistic loads.
Tiwary, Pratyush, van de Walle, Axel
core  

Accelerated Rates Regression Models for Recurrent Failure Time Data [PDF]

open access: yesLifetime Data Analysis, 2004
In this article, we formulate a semiparametric model for counting processes in which the effect of covariates is to transform the time scale for a baseline rate function. We assume an arbitrary dependence structure for the counting process and propose a class of estimating equations for the regression parameters. Asymptotic results for these estimators
openaire   +3 more sources

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