Results 191 to 200 of about 36,992 (256)

Permafrost Terrain Disturbance Susceptibility in the Nacho Nyäk Tagé (Stewart River) Watershed, Yukon, Canada

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT The Nacho Nyäk Tagé (Stewart River) watershed in central Yukon (Canada) is characterized by discontinuous permafrost that is locally highly sensitive to thaw. This study aims to map the spatial distribution of permafrost terrain disturbances (PTDs) in the watershed and model thaw susceptibility to support community‐led land‐use planning by the
Frederic Brieger, Murray Richardson, Shawn Kenny   +2 more
wiley   +1 more source

Topical CCL3 Is Well-Tolerated and Improves Liver Function in Diabetic Mice: Evidence from a 14-Day Toxicity Study. [PDF]

Cells
Dehari D, Padmakumari R, Tesfaw G, Fierro FA, Ameer GA, Shafikhani SH.   +5 more
europepmc   +1 more source

Ethnobotanical insights into the medicinal and food uses of Lamiaceae in the Mediterranean region: A systematic review and meta‐analysis

PLANTS, PEOPLE, PLANET, EarlyView.
For generations, Mediterranean communities have used Lamiaceae or Labiatae plants like rosemary, thyme or mint to care for their health and to enrich their food. By bringing together dispersed knowledge from across the Mediterranean region, our review revealed the continuing relevance of Lamiaceae while also compiling past uses that may hold future ...
Fuencisla Cáceres, Joan Vallès, Teresa Garnatje, Airy Gras   +3 more
wiley   +1 more source

Hepatitis Delta Virus Infection: An Overview. [PDF]

Pathogens
Duque V, Duque D.
europepmc   +1 more source

Establishment and Comparative Analysis of Radiation‐Induced Liver Disease in Normal and Fibrotic Rat Models

Precision Radiation Oncology, EarlyView.
This study successfully established two novel rat models of radiation‐induced liver disease (RILD), one in healthy livers and the other in TAA‐induced fibrotic livers, providing valuable insights into the combined effects of radiation and pre‐existing fibrosis.
Yanting Jiang, Yuxi Ding, Fang Wang, Danni Chen, Weixiang Zhong, Zhongjie Lu, Yixiang J. Wang, Senxiang Yan, Xiaoguang Liu, Feng Zhao   +9 more
wiley   +1 more source

Imatinib-induced rhabdomyolysis: A case report. [PDF]

Leuk Res Rep
Rubenstein J, Schwartz SM, Vankawala J, Caplan M, Shea S, Jurcic JG.   +5 more
europepmc   +1 more source

Pharmacological Inhibition of APT2 by Solasonine Promotes Ferroptosis Through Palmitoylation Modulation in Gallbladder Cancer

Phytotherapy Research, EarlyView.
Schematic illustration of SS‐induced ferroptosis through targeting APT2‐mediated STAT3 palmitoylation in GBC cells. ABSTRACT Gallbladder cancer (GBC), the most prevalent and lethal biliary tract malignancy, lacks effective therapeutic strategies. Solasonine (SS), a bioactive steroidal alkaloid derived from Solanum nigrum L, exhibits antitumor activity ...
Liu‐qing Shi, Jing‐wei Zhao, Jia‐yun Zhu, Cheng Zhao, Zi‐yi Yang, Li‐jia Pan, Ben Ma, Zheng‐yu Chen, Zi‐ying Wang, Chun‐jie Li, Shi‐lei Liu, Jia‐wei Mei, Ping Dong   +12 more
wiley   +1 more source

Evexomostat (SDX-7320), a methionine aminopeptidase type 2 inhibitor, stimulates weight loss and inhibits obesity-accelerated tumor growth. [PDF]

Front Oncol
Cornelius P, Mayes BA, Dannenberg AJ, Dufour PJ, Little S, Guzior DV, Petersen JS, Shanahan JM, Carver BJ.   +8 more
europepmc   +1 more source

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

Phytotherapy Research, EarlyView.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng, Mingyang He, Haiying Wu, Tianjie Zhang, Yuxia Jiang, Chuanwei Xin, Meiling Zhang, Jiaqi He, Lulu Zheng   +8 more
wiley   +1 more source