Targeted triggering of SORL1 expression through a novel MPOC delivery system could inhibit ccRCC progression through binding to TRIM22 and further promoting ubiquitination‐mediated C‐MYC degradation, thereby facilitating the inhibition of oxidative phosphorylation through transcriptional repression of ACO2 and IDH2.
Keyi Wang +11 more
wiley +1 more source
Statistical Denoising of Transient Rendering
Abstract Transient rendering simulates light in motion, measuring the time of flight from the light source to the camera. However, the stochastic nature of Monte Carlo is aggravated in transient rendering, since samples are now spread along the temporal domain.
Oscar Pueyo‐Ciutad +2 more
wiley +1 more source
Toxicity of external beam accelerated partial-breast irradiation (APBI) in adjuvant therapy of early-stage breast cancer: prospective randomized study. [PDF]
Burkon P +9 more
europepmc +1 more source
Abstract Employers play a key role in supporting the inclusion of unemployed people. However, organisational diversity, equity and inclusion (DEI) practices do not typically address discrimination against people experiencing unemployment. Utilising a semi‐systematic breakout review, we identify five gendered factors that contribute to the risk of ...
Helen Tracey, Mick Brookes
wiley +1 more source
Ten-Year Results of Accelerated Partial-Breast Irradiation with Interstitial Multicatheter Brachytherapy after Breast-Conserving Surgery for Low-Risk Early Breast Cancer. [PDF]
Rodríguez-Ibarria NG +7 more
europepmc +1 more source
Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley +1 more source
Long-Term Clinical and Cosmetic Outcomes of Once-Daily Accelerated Partial Breast Irradiation in Early Breast Cancer. [PDF]
Kumar R +10 more
europepmc +1 more source
ABSTRACT This study examines how issues across boundaries influence contention dynamics in a movement of movements on social media. Participants utilize social media to support or oppose goals and actions related to their visions regarding societal changes. As the boundaries of movements are fluid on social media, we investigate the actors' identities,
Carol Lee +2 more
wiley +1 more source
Improved Dosimetry and Plan Quality for Accelerated Partial Breast Irradiation Using Online Adaptive Radiation Therapy: A Single Institutional Study. [PDF]
Pogue JA +9 more
europepmc +1 more source
Molecular Links Between Heat Stress and DNA Damage Response in Plants
ABSTRACT Climate change poses a major threat to agricultural productivity and, consequently, to global food security. Among the consequences of climate change, heat stress (HS) has emerged as a critical factor limiting crop performance. This has stimulated extensive research over the past decade to elucidate the molecular and physiological mechanisms ...
Adrian Calves‐Ubach +1 more
wiley +1 more source

