Results 181 to 190 of about 6,530 (239)

Biological definition of periodontal diseases: A historical review of host‐response diagnostics and their implications for disease classification

Periodontology 2000, EarlyView.
Abstract Background Understanding periodontal diseases through a biological lens has been a central aim in periodontal research. Visionary pioneers in the field established the foundations of our knowledge, providing invaluable insights into disease mechanisms and progression.
Nagihan Bostanci, Melissa M. Grant, Moritz Kebschull   +2 more
wiley   +1 more source

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Cellular mechanisms of radiation‐induced myocyte dysfunction: effects on calcium handling, ion channel regulation and mitochondrial energetics

The Journal of Physiology, EarlyView.
Abstract figure legend Dose‐dependent effects of radiation on cardiac electrophysiology and arrhythmia susceptibility. At low radiation doses (left), increased reactive oxygen species (ROS) initiate an ROS–Ca2+ positive feedback loop involving calcium/calmodulin‐dependent protein kinase II (CaMKII) activation, enhanced L‐type Ca2+ current (ICaL ...
Hannah M. Zukowski, Colleen E. Clancy
wiley   +1 more source

Randomized trials in accelerated partial breast irradiation: "Two wrongs don't make a right!!" [PDF]

Rep Pract Oncol Radiother, 2019
Belkacemi Y, Paix A, Taghian AG.
europepmc   +1 more source

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin

The Journal of Physiology, EarlyView.
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley   +1 more source

Radiation‐Induced Skin Injury in Cancer Radiotherapy: From Mechanisms to Management

Advanced Oncology, Volume 1, Issue 1, December 2026.
Radiation‐induced skin injuries (RISI) remain a significant challenge faced by cancer patients receiving radiotherapy (RT). This perspective article examines the pathophysiology of RISI and evaluates the currently existing and emerging therapeutic strategies, including stem cell‐derived exosomes and advanced hydrogels.
Zeynep Meral Toutoungi, Nukhet Aykin‐Burns, Jingyi Chen, Younghye Song   +3 more
wiley   +1 more source

Five-Year Outcomes of a Phase 1/2 Trial of Accelerated Partial Breast Irradiation Using Proton Therapy for Women With Stage 0-IIA Breast Cancer. [PDF]

Adv Radiat Oncol
Freedman GM, Li T, Garver E, Shillington K, Shinkle B, Tchou JC, Fayanju OM, Lin L, Taunk NK.   +8 more
europepmc   +1 more source

Late Pliocene–Quaternary Arc Volcanism at the Southern Limit of the Hikurangi Subduction Zone: Revised Chronology of the Taranaki Peninsula, New Zealand

New Zealand Journal of Geology and Geophysics, Volume 69, Issue 4, December 2026.
Igneous centres across the Taranaki Peninsula represent the southwestern limit of arc volcanism associated with the Tonga–Kermadec–Hikurangi subduction system. Taranaki Maunga, the youngest and largest of three andesitic stratovolcanoes, dominates the geomorphology of the Taranaki Peninsula along with the eroded remnants of the Kaitake and Pouakai ...
G. P. Thrasher, M. W. Sagar, H. Seebeck, G. P. D. Viskovic   +3 more
wiley   +1 more source

Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang, Songhang Xing, Shanshan Zhang, Yuan Hao, Xiaojie Qu, Wurihan Bao, Manwei Hao, Han Sun, Mingyuan Dong, Huiling Zhang, Dan Huang, Yiqi Wang, Xuanjie Jiang, Xiaoyu Pu, Yanyan Chi, Xingtong Wang, Xuefeng Li   +16 more
wiley   +1 more source