Results 121 to 130 of about 1,517,049 (291)
A formulation dataset of poly(lactide-co-glycolide) nanoparticles for small molecule delivery
Poly(lactide-co-glycolide) (PLGA) nanoparticles are promising drug delivery systems, widely recognized for their ability to overcome various limitations associated with conventional formulations.
Anita Goren +3 more
doaj +1 more source
Background. In team sports, decisive actions such as anticipating opponents’ scheme executions and realizing game objectives depend on the ability to accelerate rapidly and maintain high speeds, often under external resistance and during changes of ...
Pompilio Cusano +3 more
doaj +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Rosalia Emma +15 more
doaj +1 more source
Peak match sprinting speed during soccer matches: analysing the pre- and post-peak speed dynamics
This study aimed to characterize match peak speeds, during a 20-second time window (10 seconds immediately before and after the match peak speed), in soccer matches. Twenty elite soccer players were monitored with global navigation satellite system (GNSS)
Hugo Silva +6 more
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
The structural integrity of cement concrete pavements, paramount for ensuring traffic safety and operational efficiency, faces mounting challenges from the escalating burden of heavy-duty vehicular traffic.
Pengpeng Li +3 more
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source

