Results 101 to 110 of about 671,164 (293)

Acceleration Independent Along-Track Velocity Estimation of Moving Targets [PDF]

open access: yes, 2008
In the paper a method for along-track velocity estimation of moving targets is presented. This method exploits the along-track interferometric (ATI) phase ramp of a range compressed moving target signal between two or more receiving channels.
Stefan V. Baumgartner   +3 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Recommendations for the use of clinical outcome assessments in rare disease drug development

open access: yesEClinicalMedicine
Summary: There are over 10,000 rare diseases collectively affecting an estimated 250–450 million people globally. While these diseases are rare individually, their cumulative impact on patients, families, healthcare systems, and society is substantial ...
Olalekan Lee Aiyegbusi   +50 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Digital reporting in a decentralized public health system: lessons from Indonesia’s micro PPKM experience

open access: yesFrontiers in Public Health
BackgroundDuring the COVID-19 pandemic, Indonesia implemented Micro PPKM (Community Activity Restrictions) as a decentralized public health response, coordinated through village-level command posts.
Dewi Nur Aisyah   +12 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Trailblazers in STEM: a document analysis of the accomplishments of Louis Stokes Alliances for Minority Participation alumni

open access: yesFrontiers in Education
The National Science Foundation (NSF) Louis Stokes Alliance for Minority Participation (LSAMP) has a > 30-year history of providing high impact educational experiences to undergraduates and graduate students of color in science, technology ...
Dominique Smart Graham   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Differences in respiratory wheezing between current exclusive e-cigarette users, current exclusive cigarette smokers, and never users of either product: findings from a population-based study

open access: yesHarm Reduction Journal
Background E-cigarettes have emerged as an alternative to combustible cigarettes, yet their comparative impact on respiratory symptoms remains uncertain.
Yusuff Adebayo Adebisi   +7 more
doaj   +1 more source

Multifaceted Assessment of Responsible Use and Bias in Language Models for Education

open access: yesComputers
Large language models (LLMs) are increasingly being utilized to develop tools and services in various domains, including education. However, due to the nature of the training data, these models are susceptible to inherent social or cognitive biases ...
Ishrat Ahmed   +4 more
doaj   +1 more source

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