Results 81 to 90 of about 1,517,049 (291)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Intersection of Immunity, Metabolism, and Muscle Regeneration in an Autoimmune‐Prone MRL Mouse Model
Advanced ScienceDue to the limited capacity of mammals to regenerate complex tissues, researchers have worked to understand the mechanisms of tissue regeneration in organisms that maintain that capacity.
Tran B. Ngo +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Earth Vertical Motions Disrupt Sleep and Next Day Performance
Nature and Science of SleepKyle A Kainec,1 Allison Ludwig,2 Megan Boltz,3 John G Oas,3 J. Lynn Caldwell,2 Daniel M Merfeld1,4 1Department of Otolaryngology – Head and Neck Surgery, Ohio State University Wexner Medical Center, Columbus, OH, USA; 2Leidos, Health Solutions, Reston ...
Kainec KA +5 more
doaj
Acceleration-Induced Nonlocality [PDF]
, 2003 The standard relativistic theory of accelerated reference frames in Minkowski spacetime is described. The measurements of accelerated observers are considered and the limitations of the standard theory, based on the hypothesis of locality, are pointed ...
Mashhoon, Bahram
core +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Optics Letters, 2009 We demonstrate that any two-dimensional accelerating beam can be described in a canonical form in Fourier space. In particular, we demonstrate that there is a one-to-one correspondence between complex functions in the real line (the line spectrum) and accelerating beams.
openaire +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Frontiers in EducationThe National Science Foundation (NSF) Louis Stokes Alliance for Minority Participation (LSAMP) has a > 30-year history of providing high impact educational experiences to undergraduates and graduate students of color in science, technology ...
Dominique Smart Graham +6 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source