Results 81 to 90 of about 563,475 (317)

Multimodal Smoking Cessation in a Real-Life Setting: Combining Motivational Interviewing With Official Therapy and Reduced Risk Products

Tobacco Use Insights, 2019
Background: Tobacco use is a global pandemic, affecting an estimated 1.2 billion people and resulting in substantial health burdens and associated costs.
Pasquale Caponnetto, Jennifer DiPiazza, Giorgio Carlo Cappello, Shirin Demma, Marilena Maglia, Riccardo Polosa   +5 more
doaj   +1 more source

Accelerators and Their Ghosts [PDF]

, 2017
Proceedings of the 8th Int.
Rescic, M., Seviour, Rebecca, Blokland,, W.   +2 more
openaire   +1 more source

Solar flare particle acceleration in collapsing magnetic traps

, 2012
Electronic redacted version excludes material for which permission has not been granted by the rights holderThe topic of this thesis is a detailed investigation of different aspects of the particle acceleration mechanisms operating in Collapsing Magnetic
Grady, Keith J.
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Intersection of Immunity, Metabolism, and Muscle Regeneration in an Autoimmune‐Prone MRL Mouse Model

Advanced Science
Due to the limited capacity of mammals to regenerate complex tissues, researchers have worked to understand the mechanisms of tissue regeneration in organisms that maintain that capacity.
Tran B. Ngo, Aditya Josyula, Sabrina DeStefano, Daphna Fertil, Mondreakest Faust, Ravi Lokwani, Kaitlyn Sadtler   +6 more
doaj   +1 more source

Demo 06-01 Angular Acceleration Machine

, 2001
This device illustrates the application of the rotational analog of Newton's second law, t = I a. Two weights can be positioned symmetrically along an arm that rotates in a vertical plane around its center, varying the moment of inertia of the rotating

core  

Oscillating mushrooms : adiabatic theory for a non-ergodic system [PDF]

, 2014
Can elliptic islands contribute to sustained energy growth as parameters of a Hamiltonian system slowly vary with time? In this paper we show that a mushroom billiard with a periodically oscillating boundary accelerates the particle inside it ...
Turaev, D, Gelfreich, V, Rom-Kedar, Vered, Turaev, Dmitry, Gelfreich, Vassili, Rom-Kedar, V   +5 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Earth Vertical Motions Disrupt Sleep and Next Day Performance

Nature and Science of Sleep
Kyle A Kainec,1 Allison Ludwig,2 Megan Boltz,3 John G Oas,3 J. Lynn Caldwell,2 Daniel M Merfeld1,4 1Department of Otolaryngology – Head and Neck Surgery, Ohio State University Wexner Medical Center, Columbus, OH, USA; 2Leidos, Health Solutions, Reston ...
Kainec KA, Ludwig A, Boltz M, Oas JG, Caldwell JL, Merfeld DM   +5 more
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source