Results 51 to 60 of about 563,475 (317)

Gravitomagnetic accelerators [PDF]

open access: yesPhysics Letters A, 2011
4 pages, 2 figures; v2: reference added; v3: slightly expanded version accepted for publication in Phys.
Chicone, Carmen Charles   +1 more
openaire   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

AKR breakup and auroral particle acceleration at substorm onset [PDF]

open access: yes, 2008
The dynamical behavior of auroral kilometric radiation (AKR) is investigated in connection with auroral particle acceleration at substorm onsets using high-time-resolution wave spectrograms provided by Polar/PWI electric field observations.
Morioka, A.   +10 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Advanced Approaches to High Intensity Laser-Driven Ion Acceleration [PDF]

open access: yes, 2010
Since the pioneering work that was carried out 10 years ago, the generation of highly energetic ion beams from laser-plasma interactions has been investigated in much detail in the regime of target normal sheath acceleration (TNSA). Creation of ion beams
Henig, A., Henig, Andreas
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Cytotoxicity, mutagenicity and genotoxicity of electronic cigarettes emission aerosols compared to cigarette smoke: the REPLICA project

open access: yesScientific Reports, 2023
Concerns have recently increased that the integrity of some scientific research is questionable due to the inability to reproduce the claimed results of some experiments and thereby confirm that the original researcher's conclusions were justified.
Rosalia Emma   +15 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Monitoring Flamenco Dance Movement with Accelerometers: Methodological and Practical Commendations

open access: yesRevista del Centro de Investigación Flamenco Telethusa, 2023
Accelerometers are tools specifically engineered for quantifying differences in force or acceleration over time, providing data regarding the magnitudes and frequency of movement.
Ningyi Zhang   +5 more
doaj   +1 more source

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