Results 91 to 100 of about 264,692 (309)

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Performance of Single Degree of Freedom (SDOF) Systems Subjected to The Near-Fault Earthquakes

مجلة النهرين للعلوم الهندسية
This paper aims to assess the structures' seismic response with a system of Single-degree-of-freedom exposed to near-fault earthquakes, taking into account the effect of pulse period, shear wave velocity (VS30), and fault mechanism. Strong ground motion
Ayah Hameed Mhawish, Hussam K. Reisn
doaj   +1 more source

Serial Correlations in Single-Subject fMRI with Sub-Second TR

, 2017
When performing statistical analysis of single-subject fMRI data, serial correlations need to be taken into account to allow for valid inference. Otherwise, the variability in the parameter estimates might be under-estimated resulting in increased false ...
Barth, Markus, Bollmann, Saskia, Cunnington, Ross, Pucket, Alexander M.   +3 more
core   +1 more source

Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress [PDF]

, 2014
It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with electron and ...
Bolton, P. R., Ledingham, K. W. D., Ma, C-M., Shikazono, N.   +3 more
core   +3 more sources

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

The Acceleration Response Spectrum for Simulated Strong Motions Considering the Earthquake Characteristics of the Korean Peninsula [PDF]

Journal of the Korean earth science society, 2007
The response spectrum is one of the important basic materials for the aseismic design. Numerous strong ground motions based on the seismic source characteristics for the earthquakes occurring in the Korean Peninsula were simulated to obtain the response spectra by using the computer program, SMSIM, developed by Boore (2005).
openaire   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

A Computationally Efficient Ground-Motion Selection Algorithm for Matching a Target Response Spectrum Mean and Variance [PDF]

, 2011
Dynamic structural analysis often requires the selection of input ground motions with a target mean response spectrum. The variance of the target response spectrum is usually ignored or accounted for in an ad hoc manner, which can bias the structural ...
Baker, Jack W., Jayaram, Nirmal, Lin, Ting   +2 more
core   +2 more sources

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

A Comparative Study on the Design Spectra Defined by Several Codes of Practice on RC Building Located in Baghdad City

مجلة النهرين للعلوم الهندسية, 2017
This paper studies the effect of different design spectral response acceleration parameters as suggested by the uniform building code (UBC), unified facilities criteria (UFC), and Iraqi seismic code(1997) (ISC 97) on the seismic response of reinforced ...
Husain Khalaf Jarallah, Zahir Noori M. Taki   +1 more
doaj