Results 31 to 40 of about 44,282 (251)

Peak floor acceleration demand prediction based on response spectrum analysis of various sophistication [PDF]

open access: yesActa Mechanica, 2016
This paper addresses the prediction of the median peak floor total acceleration (PFA) demand in spatial elastic structures subjected to seismic excitation. The prediction is based on various response spectrum methods of different degrees of sophistication.
Moschen, Lukas, Adam, Christoph
openaire   +2 more sources

Towards improving the seismic hazard map and the response spectrum for the state of RN/Brazil

open access: yesRevista IBRACON de Estruturas e Materiais, 2021
Although Brazilian seismic activity is defined as low to moderate, it is known that intraplate earthquakes can also be associated to high intensities. In Brazil, the state of Rio Grande do Norte (RN) is one of the most seismically active areas, but there
Petrus Gorgônio Bulhões da Nóbrega   +2 more
doaj   +1 more source

Analysis of the local site effect in Longtoushan town

open access: yes地震科学进展, 2022
Based on the drilling data of six typical sites in Longtoushan town and the test data of dynamic nonlinear characteristics of soil, the seismic response analysis models of the corresponding sites were established respectively.
Zhen Chen   +6 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Preliminary analysis of seismic performance of a shear wall structure in Qinghai Maduo M7.4 earthquake

open access: yes地球与行星物理论评, 2022
In this paper, the measured acceleration of Dawu station of the M7.4 earthquake in Maduo County, Qinghai Province on May 22, 2021 and the acceleration at Yematan bridge simulated by our research group with the empirical Green's function method are ...
Bo Zhang   +3 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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