Results 71 to 80 of about 264,692 (309)

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Measuring the Broad-band X-Ray Spectrum from 400 eV to 40 keV in the Southwest Part of the Supernova Remnant RX J1713.7-3946

open access: yes, 2007
We report on results from Suzaku broadband X-ray observations of the southwest part of the Galactic supernova remnant (SNR) RX J1713.7-3946 with an energy coverage of 0.4-40 keV.
Bamba, Aya   +15 more
core   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Analyses of strong motion earthquake accelerograms, Volume III - Response spectra; Part F - Accelerograms IIF086 through IIF105 [PDF]

open access: yes, 1973
This is the sixth report of a series presenting earthquake response spectrum curves calculated from corrected ground accelerograms. In the Preface to the first part, Volume III, Part A, Report No.
Earthquake Engineering Research Laboratory,
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Determination of design spectrum compatible evolutionary spectra via Monte Carlo peak factor estimation [PDF]

open access: yes, 2009
The problem of generating ensembles of artificial non-stationary earthquake accelerograms compatible with a given (target) response/design spectrum is cast on a stochastic basis.
Giaralis, A., Spanos, P. D.
core  

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

适用于全周期结构的速度脉冲型地震动强度表征参数研究

open access: yesDizhen xuebao, 2019
鉴于传统的地震动强度表征参数(IM)不能有效地反映速度脉冲型地震动的破坏特征,需要研究能够在全周期段内表征速度脉冲型地震动强度的参数。本文首先从NGA-West2强震数据库中选取了236条速度脉冲记录,分析了42种地震动参数之间的相似性和相关性,初步给出了速度脉冲型地震动强度的表征参数;其次,利用单自由度体系动力时程分析方法,研究了不同延性μ条件下速度脉冲型地震动强度表征参数与最大非线性位移um之间的相关性系数随周期T的变化特征 ...
Xiaofen Zhao   +3 more
doaj   +1 more source

Ride quality meter [PDF]

open access: yes, 1983
A ride quality meter is disclosed that automatically transforms vibration and noise measurements into a single number index of passenger discomfort. The noise measurements are converted into a noise discomfort value.
Clevenson, S. A.   +3 more
core   +1 more source

A Novel Approach in Constraining Electron Spectra in Blazar Jets: The Case of Markarian 421

open access: yes, 2010
We report results from the observations of the well studied TeV blazar Mrk 421 with the Swift and the Suzaku satellites in December 2008. During the observation, Mrk 421 was found in a relatively low activity state, with the corresponding 2-10 keV flux ...
Hayashida, M.   +9 more
core   +1 more source

Home - About - Disclaimer - Privacy