Results 31 to 40 of about 50,210 (255)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Inexpensive and Automatic Calibration for Acceleration Sensors [PDF]

open access: yes, 2005
In this paper, we present two methods for calibration of acceleration sensors that are inexpensive, in-situ, require minimum user interaction and are targeted to a broad set of acceleration sensor applications and devices. We overcome the necessity of orthogonal axes alignment by extending existing calibration methods with a non-orthogonal axes model ...
Krohn, Albert   +5 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Gait Analysis Using Walking-Generated Acceleration Obtained from Two Sensors Attached to the Lower Legs

open access: yesSensors
Gait evaluation approaches using small, lightweight inertial sensors have recently been developed, offering improvements in terms of both portability and usability.
Ayuko Saito   +5 more
doaj   +1 more source

Six-Degree-of-Freedom Sensor Fish Design and Instrumentation

open access: yesSensors, 2007
Fish passing through dams may be injured or killed despite advances in turbinedesign, project operations and other fish bypass systems. The six-degree-of-freedom (6DOF)Sensor Fish device is an autonomous sensor package that characterizes the physical ...
Marshall C. Richmond   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Assessment of daily physical activities with sensors attached to the upper limbs in healthy adults using a manual wheelchair

open access: yesJournal of Physical Fitness and Sports Medicine, 2018
This study examined the energy expenditure (EE) of healthy adults during typical use of a manual wheelchair by attaching sensors to the subjects’ upper limbs.
Ryuji Takigawa   +4 more
doaj   +1 more source

Research on HAR-Based Floor Positioning

open access: yesISPRS International Journal of Geo-Information, 2021
Floor positioning is an important aspect of indoor positioning technology, which is closely related to location-based services (LBSs). Currently, floor positioning technologies are mainly based on radio signals and barometric pressure.
Hongxia Qi   +4 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

A study on sensor position for thigh and lower leg motion sensors during walking (Focusing on the knee sagittal plane angle)

open access: yesNihon Kikai Gakkai ronbunshu, 2018
This paper describes the use of nine-axis motion sensors to evaluate the motion sensor position on the thigh and lower leg during walking. The motion sensors are mounted on a subject's body using adhesive tape.
Ayuko SAITO   +3 more
doaj   +1 more source

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