Results 31 to 40 of about 50,575 (247)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Research on HAR-Based Floor Positioning

open access: yesISPRS International Journal of Geo-Information, 2021
Floor positioning is an important aspect of indoor positioning technology, which is closely related to location-based services (LBSs). Currently, floor positioning technologies are mainly based on radio signals and barometric pressure.
Hongxia Qi   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Gait Analysis Using Walking-Generated Acceleration Obtained from Two Sensors Attached to the Lower Legs

open access: yesSensors
Gait evaluation approaches using small, lightweight inertial sensors have recently been developed, offering improvements in terms of both portability and usability.
Ayuko Saito   +5 more
doaj   +1 more source

Six-Degree-of-Freedom Sensor Fish Design and Instrumentation

open access: yesSensors, 2007
Fish passing through dams may be injured or killed despite advances in turbinedesign, project operations and other fish bypass systems. The six-degree-of-freedom (6DOF)Sensor Fish device is an autonomous sensor package that characterizes the physical ...
Marshall C. Richmond   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Assessment of daily physical activities with sensors attached to the upper limbs in healthy adults using a manual wheelchair

open access: yesJournal of Physical Fitness and Sports Medicine, 2018
This study examined the energy expenditure (EE) of healthy adults during typical use of a manual wheelchair by attaching sensors to the subjects’ upper limbs.
Ryuji Takigawa   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Deep Convolutional Neural Network-Based Hemiplegic Gait Detection Using an Inertial Sensor Located Freely in a Pocket

open access: yesSensors, 2022
In most previous studies, the acceleration sensor is attached to a fixed position for gait analysis. However, if it is aimed at daily use, wearing it in a fixed position may cause discomfort.
Hangsik Shin
doaj   +1 more source

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