Results 51 to 60 of about 253,835 (247)

Acceleration disturbances and requirements for ASTROD I

, 2006
ASTRODynamical Space Test of Relativity using Optical Devices I (ASTROD I) mainly aims at testing relativistic gravity and measuring the solar-system parameters with high precision, by carrying out laser ranging between a spacecraft in a solar orbit and ...
, Anza S, Balogh A, Bao G, Bec-Borsenberger A, Bender P, Blaser J P, Cavalleri A, Dolesi R, Fichter W, Gill D K, Hammesfahr A, Hanson J, Jackson J D, Jafry Y, Lang K R, Ni W-T, Ni W-T, Rodrigues M, Rüdiger A, Sachie Shiomi, Schumaker B L, Schumaker B L, Shaul D N A, Shiomi S, Silvestri Z, Speake C C, Speake C C, Stebbins R T, Touboul P, Vitale S, Vitale S, Vitale S, Vitale S, Weber W J Cruise M Saulson P, Wei-Tou Ni, Worden P, Xia Y, Zhou Z B   +38 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Structural health monitoring and bridge condition assessment [PDF]

, 2016
Thesis (Ph.D.) University of Alaska Fairbanks, 2016This research is mainly in the field of structural identification and model calibration, optimal sensor placement, and structural health monitoring application for large-scale structures.
Xiao, Feng, 肖枫
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Performance Evaluation of Inverted Tee (IT) Bridge System [PDF]

, 2019
The Inverted Tee (IT) girder bridge system was originally developed in 1996 by the University of Nebraska–Lincoln (UNL) researchers and Nebraska Department of Transportation (NDOT) engineers.
Abo El-Khier, Mostafa, Kodsy, Antony Mohsen Kamal Masoud, Martindale, Garrett P, Morcous, George, Watson, Daniel, Wood, Richard L.   +5 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Semi-wildlife gait patterns classification using Statistical Methods and Artificial Neural Networks [PDF]

, 2017
Several studies have focused on classifying behavioral patterns in wildlife and captive species to monitor their activities and so to understanding the interactions of animals and control their welfare, for biological research or commercial purposes.
Domínguez Morales, Juan Pedro, Domínguez Morales, Manuel Jesús, Gutiérrez Galán, Daniel, Gómez Rodríguez, Francisco de Asís, Jiménez Fernández, Ángel Francisco, Linares Barranco, Alejandro, Miró Amarante, María Lourdes, Rivas Pérez, Manuel   +7 more
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source