Results 71 to 80 of about 50,210 (255)

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Vibration characteristics of the two-stage throttle valve induced by cavitation

open access: yesThe Journal of Engineering, 2018
The effect of cavitation on vibration characteristics of a two-stage throttle valve is experimentally studied by changing inlet pressure, outlet pressure and opening.
Beibei Li   +4 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Application of unconstrained BCG extraction in VDT visual fatigue monitoring

open access: yesThe Journal of Engineering, 2019
Eye diseases caused by long times of use of visual display terminal (VDT) products is considered as a serious problem in recent years. The eye fatigue monitoring is significant for early warning. Here, an unconstrained measuring method is used to extract
Yongxiang Jiang   +6 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Fabrication and Characterization of Monolithic Integrated Three-Axis Acceleration/Pressure/Magnetic Field Sensors

open access: yesMicromachines
In order to realize the measurement of three-axis acceleration, pressure, and magnetic field, monolithic integrated three-axis acceleration/pressure/magnetic field sensors are proposed in this paper.
Ying Wang   +3 more
doaj   +1 more source

Development of mine-used signal conditioning device of vibration acceleration sensor

open access: yesGong-kuang zidonghua, 2014
In view of problem that vibration signal of underground large equipments is difficult to be collected, a mine-used signal conditioning device of vibration acceleration sensor was designed.
JI Xiaodong   +3 more
doaj   +1 more source

A new L-shaped rigid beam FBG acceleration sensor. [PDF]

open access: yesSci Rep, 2022
Teng Y   +5 more
europepmc   +1 more source

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