Results 71 to 80 of about 253,667 (293)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Multi-sensor Acceleration-Based Action Recognition [PDF]

, 2014
In this paper, a framework to recognize human actions from acceleration data is proposed. An important step for an accurate recognition is the pre-processing of input data and the following classification by the machine learning algorithm. In this paper, we suggest to combine Dynamic Time Warping (DTW) with Random Forest.
Baumann, Florian, Schulz, Irina, Rosenhahn, Bodo   +2 more
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Laboratory evaluation of a low‐cost micro electro‐mechanical systems sensor for inclination and acceleration monitoring

Deep Underground Science and Engineering
In this study, the design and development of a sensor made of low‐cost parts to monitor inclination and acceleration are presented. Α micro electro‐mechanical systems, micro electro mechanical systems, sensor was housed in a robust enclosure and ...
Antonis Paganis, Vassiliki N. Georgiannou, Xenofon Lignos, Reina El Dahr   +3 more
doaj   +1 more source

Analysis of vibration characteristics of cutting arm of EML340 continuous miner

Gong-kuang zidonghua, 2016
In order to get vibration characteristics of cutting arm of continuous miner in working condition, the optimized sensor disposition was done taking results of the modal movement energy as main reference and results of modal strain energy as auxiliary ...
ZHANG Yanjun, WANG Junyuan, DONG Lei, DU Wenhua, LI Yong, WANG Shengli   +5 more
doaj   +1 more source

Rim inertial measuring system [PDF]

, 1981
The invention includes an angular momentum control device (AMCD) having a rim and several magnetic bearing stations. The AMCD is in a strapped down position on a spacecraft.
Anderson, W. W., Groom, N. J., Phillips, W. H.   +2 more
core   +1 more source

Hybridizing matter-wave and classical accelerometers

, 2014
We demonstrate a hybrid accelerometer that benefits from the advantages of both conventional and atomic sensors in terms of bandwidth (DC to 430 Hz) and long term stability. First, the use of a real time correction of the atom interferometer phase by the
Hardin, Thomas, Landragin, Arnaud, Lautier, Jean, Lours, Michel, Merlet, Sebastien, Santos, Franck Pereira Dos, Volodimer, Laurent   +6 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Investigation of analysis method of prosthetic running using motion sensors (Derivation of ground reaction force estimation value through all running process)

Nihon Kikai Gakkai ronbunshu, 2018
This study proposes a method to measure ground force outside the laboratory using motion sensors. The authors estimated ground reaction force (GRF) from the measurements obtained by a motion sensor at an athletics track with no force plates installed ...
Motohiko TAKAHASHI, Ryoji ONODERA, Junji KATSUHIRA, Ryotaro HONTE, Koutaro TERADA, Hironori SUDA, Yu MAEDA, Nobuharu MIMURA   +7 more
doaj   +1 more source