Results 131 to 140 of about 392,882 (300)
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
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Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
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Образование и наука, 2018 Introduction. Modern trends in the development of education and society as a whole not only strengthen the role of modern universities in transformation of the social sphere, but also require a new approach to developing skills and over-professional ...
E. G. Syryamkina +2 more
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IEEE Transactions on Nuclear Science, 1983 Laser accelerators may be conveniently characterized, by their mode of operation, into media, far-field, and near-field accelerators. The first category--media accelerators--include the Inverse Cherenkov Effect Accelerator, the Plasma Focus Accelerator, and the Beat Wave Accelerator (BWA).
openaire +3 more sources
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Development of an automated system for the operation of an electron beam accelerator
Brazilian Journal of Radiation Sciences, 2019 Electron beam accelerators are used in many applications, such as basic physical research, chemistry, medicine, molecular biology, microelectronics, agriculture and industry, among others.
Samir Luiz Somessari
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
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Business-catalysts as Drivers of Regional Innovation Systems
Foresight and STI Governance, 2015 The need to address the tremendous technological and investment risks intrinsic to the stages of business structuring and drawing up a business model means that an optimal tool to support innovative start-ups is sought.
Sergey Makarov, Ekaterina Ugnich
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
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