Results 151 to 160 of about 652,834 (343)
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Ion Acceleration - Target Normal Sheath Acceleration
, 2016 Energetic ions have been observed since the very first laser-plasma experiments.Their origin was found to be the charge separation of electrons heated by thelaser, which transfers energy to the ions accelerated in the field. The adventof ultra-intense lasers with pulse lengths in the femtosecond regime resulted inthe discovery of very energetic ions ...
Roth, M., Schollmeier, M.
openaire +2 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
The Current Development Status in Accelerator Preparation of Radionuclide 68Ge
Journal of IsotopesIn recent years，the PET imaging with 68Ga-labeled radiopharmaceuticals have grown significantly，which is driven by the popularity of 68Ge-68Ga generator，the development of targeted tracers，simple labeling procedures，and approval of 68Ga-labeled ...
Ziyu ZHAO +5 more
doaj +1 more source
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
The Financial Accelerator in a Quantitative Business Cycle Framework
, 1998 B. Bernanke +4 more
semanticscholar +1 more source