Results 161 to 170 of about 392,882 (300)

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Green upgrading of SPring-8 to produce stable, ultrabrilliant hard X-ray beams

open access: yesJournal of Synchrotron Radiation
SPring-8-II is a major upgrade project of SPring-8 that was inaugurated in October 1997 as a third-generation synchrotron radiation light source. This upgrade project aims to achieve three goals simultaneously: achievement of excellent light source ...
Hitoshi Tanaka   +42 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

SPIRAL2 accelerator construction progress [PDF]

open access: yes, 2012
TH2A02 - ISBN 878-3-95450-122-9International audienceThe installation of the SPIRAL2 superconducting accelerator at GANIL is almost started. All the major components have been tested in the various partner laboratories, and the building construction is ...
Bertrand, Pierre, Ferdinand, R.
core   +1 more source

Application of local area networks to accelerator control systems at the Stanford Linear Accelerator [PDF]

open access: yes, 1983
The history and current status of SLAC's SDLC networks for distributed accelerator control systems are discussed. These local area networks have been used for instrumentation and control of the linear accelerator.
Melen, R., Linstadt, E., Fox, J.D.
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

PAMELA Overview : design goals and principles [PDF]

open access: yes, 2009
The PAMELA (Particle Accelerator for MEdicaL Applications) project is to design an accelerator for proton and light ion therapy using non-scaling Fixed Field Alternating Gradient (FFAG) accelerators, as part of the CONFORM project, which is also ...
Easton, M.J.   +27 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

The Influence of Bolted-flange Connection on the Coaxial Tolerance in Accelerator Centering Assembling

open access: yes工程科学与技术, 2007
:In view of the high demand on the coaxial tolerance of linear induction accelerator in centering assembling and considering the interaction among flange, bolts and gasket, finite element analysis was adopted and a 3-D finite element model of accelerator
doaj  

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