Results 111 to 120 of about 2,234,030 (304)

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

CAS Advanced Accelerator Physics, 6-18 November 2022, Sevrier, France

, 2022
This lecture provides hands-on guidance for performing optics calculations related to a simple synchrotron. It walks users through the steps needed to execute these calculations using the xsuite, a software for accelerator simulations.
Sterbini, Guido
core  

R&D PROPOSAL FOR THE NATIONAL MUON ACCELERATOR PROGRAM [PDF]

, 2010
This document contains a description of a multi-year national R&D program aimed at completing a Design Feasibility Study (DFS) for a Muon Collider and, with international participation, a Reference Design Report (RDR) for a muon-based Neutrino Factory ...
Program, Muon Accelerator, Zisman, Michael S., Geer, Stephen   +2 more
core   +1 more source

Introduction to Accelerator Physics [PDF]

, 2015
The development of charged particle accelerators and it’s underlying principles has its basis on the theoretical and experimental progress in fundamental physical phenomena. While active particle accelerator experimentation started seriously only in the twentieth century, it depended on the basic physical understanding of electromagnetic phenomena as ...
openaire   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Controls Abstraction Towards Accelerator Physics: A Middle Layer Python Package for Particle Accelerator Control

Control system middle layers act as a co-ordination and communication bridge between end users, including operators, system experts, scientists, and experimental users, and the low-level control system interface.
J. K. Jones, F. Jackson, D. J. Scott, N. Ziyan, C. Garnier, M. A. Johnson, Matthew King, T. Kabana, R. Roussel, A. D. Brynes, K. Baker, S. Chowdhury, N. Neveu, Brynes AD, Chowdhury S, Jones JK, Scott DJ, Ziyan N, King M, Johnson MA, Jackson F, Kabana T, Neveu N, Baker K, Roussel R, Garnier C   +25 more
core   +1 more source

Major Accelerator Facilities for Nuclear Physics in Asia Pacific

, 2019
Asian Nuclear Physics Association (ANPhA) is the central organization representing nuclear physics in Asia Pacific. ANPhA is now preparing a list of accelerator facilities applicable for nuclear physics experiments in Asia Pacific.
Kazuhiro Tanaka, Tanaka, K
core   +1 more source

Modeling Progressive Brain Volume Losses in Chronic Moderate Severe Traumatic Brain Injury: Extensive, but Attenuating

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green, Brenda Colella, Alana Changoor, David J. Mikulis, Adrienne Li, Kadeen Johns, Georges A. Monette   +6 more
wiley   +1 more source

Future possibilities with Fermilab neutrino beams [PDF]

, 2008
We will start with a brief overview of neutrino oscillation physics with emphasis on the remaining unanswered questions. Next, after mentioning near future reactor and accelerator experiments searching for a non zero {theta}{sub 13}, we will introduce ...
Saoulidou, Niki, Niki Saoulidou
core   +1 more source

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph, Megan McCune, Riley Bove, Ahmed Abdelhak, Bruce A. C. Cree, Valerie J. Block   +5 more
wiley   +1 more source