Results 91 to 100 of about 1,178,511 (339)

Accelerator physics code web repository [PDF]

, 2006
In the framework of the CARE HHH European Network, we have developed a web-based dynamic accelerator-physics code repository. We describe the design, structure and contents of this repository, illustrate its usage, and discuss our future plans, with ...
Todesco, E., Oide, K., Pieloni, T., Schmidt, F., Sen, T., Zimmermann, F., Bellodi, G., Ohmi, K., Giovannozzi, M., Ruggiero, F., Farvacque, L., Benedetto, E., Bartolini, R., Dorda, U., Payet, J., Papaphilippou, Y., Zotter, B. W., Furman, M., Basset, R., Rumolo, G., Chin, Y. H.   +20 more
core  

The scanning electron microscope as an accelerator for the undergraduate advanced physics laboratory [PDF]

, 2010
Few universities or colleges have an accelerator for use with advanced physics laboratories, but many of these institutions have a scanning electron microscope (SEM) on site, often in the biology department.
Floyd D. McDaniel, Randolph S. Peterson, Barney L. Doyle, Mark Mondol, Mondol, Mark K., Berggren, Karl K., Peterson, Randolph S., Karl K. Berggren   +7 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Subradiant spontaneous undulator emission through collective suppression of shot noise

Physical Review Special Topics. Accelerators and Beams, 2015
The phenomenon of Dicke’s subradiance, in which the collective properties of a system suppress radiation, has received broad interest in atomic physics.
D. Ratner, E. Hemsing, A. Gover, A. Marinelli, A. Nause   +4 more
doaj   +1 more source

Zeptosecond dynamics of superheavy element synthesis reactions: The role of sequential fission [PDF]

EPJ Web of Conferences
Our understanding of quasifission and thus superheavy element formation may be hindered by sequential fission, a secondary process that results in three final quasifission fragments rather than the expected two.
Hayles S.L., Buete J., Cook K.J., Hinde D.J., Dasgupta M., Bezzina L.T., Haba H., Lakelin M.K., Lee H., Seabra C.C., Tran T., Webber M.M.   +11 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Velocity dispersion of correlated energy spread electron beams in the free electron laser

New Journal of Physics, 2017
The effects of a correlated linear energy/velocity chirp in the electron beam in the free electron laser (FEL), and how to compensate for its effects by using an appropriate taper (or reverse-taper) of the undulator magnetic field, is well known.
L T Campbell, A R Maier
doaj   +1 more source