Results 71 to 80 of about 1,309,305 (327)

Emittance preservation in a plasma-wakefield accelerator [PDF]

Nature Communications
Radio-frequency particle accelerators are engines of discovery, powering high-energy physics and photon science, but are also large and expensive due to their limited accelerating fields.
C. Lindstrøm, J. Beinortaitė, J. Björklund Svensson, L. Boulton, J. Chappell, S. Diederichs, B. Foster, J. Garland, P. González Caminal, G. Loisch, F. Peña, S. Schröder, M. Th'evenet, S. Wesch, M. Wing, J. C. Wood, R. D’Arcy, J. Osterhoff   +17 more
semanticscholar   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Physics Needs for Future Accelerators [PDF]

Lepton and Photon Interactions at High Energies, 2000
19 pages, 7 figures. Talk presented at the XIX International Symposium on Lepton and Photon Interactions at High Energies (Lepton-Photon '99), Stanford University, August 9-14 ...
openaire   +2 more sources

The High-Luminosity upgrade of the LHC: Physics and Technology Challenges for the Accelerator and the Experiments

, 2016
In the second phase of the LHC physics program, the accelerator will provide an additional integrated luminosity of about 2500/fb over 10 years of operation to the general purpose detectors ATLAS and CMS. This will substantially enlarge the mass reach in
B. Schmidt
semanticscholar   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Searches for decays of new particles in the DUNE Multi-Purpose near Detector

Journal of High Energy Physics, 2020
One proposed component of the upcoming Deep Underground Neutrino Experiment (DUNE) near detector complex is a multi-purpose, magnetized, gaseous argon time projection chamber: the Multi-Purpose Detector (MPD).
Jeffrey M. Berryman, André de Gouvêa, Patrick J. Fox, Boris J. Kayser, Kevin J. Kelly, Jennifer L. Raaf   +5 more
doaj   +1 more source

Non-accelerator particle physics [PDF]

, 1991
The goals of this research are the experimental testing of fundamental theories of physics such as grand unification and the exploration of cosmic phenomena through the techniques of particle physics. We are working on the MACRO experiment, which employs a large area underground detector to search for grand unification magnetic monopoles and dark ...
Steinberg, R.I., Lane, C.E.
openaire   +2 more sources

Illinois Accelerator Research Center

, 2017
The Illinois Accelerator Research Center (IARC) hosts a new accelerator development program at Fermi National Accelerator Laboratory. IARC provides access to Fermi's state-of-the-art facilities and technologies for research, development and ...
Cooper, Charlie A, Kroc, Thomas K.
core   +1 more source

Physics beyond colliders at CERN: beyond the Standard Model working group report [PDF]

Journal of Physics G: Nuclear and Particle Physics, 2019
The Physics Beyond Colliders initiative is an exploratory study aimed at exploiting the full scientific potential of the CERN's accelerator complex and scientific infrastructures through projects complementary to the LHC and other possible future ...
J. Beacham, C. Burrage, D. Curtin, A. De Roeck, J. Evans, J. Feng, C. Gatto, S. Gninenko, A. Hartin, I. Irastorza, J. Jaeckel, K. Jungmann, K. Kirch, F. Kling, S. Knapen, M. Lamont, G. Lanfranchi, C. Lazzeroni, A. Lindner, F. Martinez-Vidal, M. Moulson, N. Neri, M Papucci, I. Pedraza, K. Petridis, M. Pospelov, A. Rozanov, G. Ruoso, P. Schuster, Y. Semertzidis, T. Spadaro, C. Vallée, G. Wilkinson   +32 more
semanticscholar   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source