Results 61 to 70 of about 1,309,305 (327)

Some frontiers of accelerator physics [PDF]

AIP Conference Proceedings, 1991
Two topics on the frontier of accelerator physics are discussed. The principles of operation and reasons for using free electron lasers are discussed. Linear electron‐positron colliders are also discussed.(AIP)
openaire   +4 more sources

Amplitude dependent orbital period in alternating gradient accelerators

, 2016
Orbital period in a ring accelerator and time of flight in a linear accelerator depend on the amplitude of betatron oscillations. The variation is negligible in ordinary particle accelerators with relatively small beam emittance.
Berg, J. S., Edmonds, C. S., Garland, J. M., Jones, J. K., Kelliher, D. J., Kirkman, I. W., Machida, S., Muratori, B. D.   +7 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Beam-Beam Effects

, 2016
One of the most severe limitations in high-intensity particle colliders is the beam-beam interaction, i.e. the perturbation of the beams as they cross the opposing beams.
Herr, W., Pieloni, T.
core   +1 more source

Conformal Bulk Fields, Dark Energy and Brane Dynamics [PDF]

, 2003
In the Randall-Sundrum scenario we analyze the dynamics of a spherically symmetric 3-brane when the bulk is filled with matter fields. Considering a global conformal transformation whose factor is the $Z_2$ symmetric warp we find a new set of exact ...
A Chamblin, A Kamenshchik, A Karch, B Carter, C Csáki, C Csáki, E Elizalde, IZ Rothstein, J Garriga, J Garriga, J Maldacena, L Randall, L Randall, MC Bento, N Dadhich, N Kaloper, O Wolf De, P Kanti, P Kanti, P Kanti, R Emparan, R Emparan, R Gregory, R Maartens, R Neves, R Neves, R Neves, RC Myers, S Giddings, SS Deshingkar, T Shiromizu, T Tanaka, WD Goldberger   +32 more
core   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Applying Bayesian inference and deterministic anisotropy to retrieve the molecular structure ∣Ψ(R)∣2 distribution from gas-phase diffraction experiments

Communications Physics, 2023
Currently, our general approach to retrieving molecular structures from ultrafast gas-phase diffraction heavily relies on complex ab initio electronic or vibrational excited state simulations to make conclusive interpretations.
Kareem Hegazy, Varun Makhija, Phil Bucksbaum, Jeff Corbett, James Cryan, Nick Hartmann, Markus Ilchen, Keith Jobe, Renkai Li, Igor Makasyuk, Xiaozhe Shen, Xijie Wang, Stephen Weathersby, Jie Yang, Ryan Coffee   +14 more
doaj   +1 more source

Underground Neutrino Detectors for Particle and Astroparticle Science: the Giant Liquid Argon Charge Imaging ExpeRiment (GLACIER)

, 2009
The current focus of the CERN program is the Large Hadron Collider (LHC), however, CERN is engaged in long baseline neutrino physics with the CNGS project and supports T2K as recognized CERN RE13, and for good reasons: a number of observed phenomena in ...
, , , , Acquafredda R . [OPERA Collaboration], Acquistapace G, Alciati M L, André Rubbia, Ankowski A [ICARUS Collaboration], Ardellier F, ArgoNeuT, Arneodo F [ICARUS Collaboration], Autiero D, Ayres D S [NOvA Collaboration], Badertscher A, Badertscher A, Badertscher A, Baldy R, Ball A E, Bandyopadhyay A [ISS Physics Working Group], Bechetoille E, Boccone V [The ArDM Collaboration], Bondar A, Bueno A, Bueno A, Bueno A, Bueno A, Bueno A, Bueno A, Bueno A, Campanelli M, Cennini P, Cline D B, Cocco A G, Eyssa, Fujii Y, Ge Y, Geer S, Gil I Botella, I Gil-Botella, Itow Y, Kodama K . [OPERA Collaboration], Komatsu M, Koshiba M, Kubota S, Meddahi M, Meregaglia A, Meregaglia A, MicroBOONE, Nath P, Nath P, Otiougova P, Pati J C, Pontecorvo B, Pontecorvo B, Pontecorvo B, Pontecorvo B, Pontecorvo B, Rubbia A, Rubbia A, Rubbia A, Rubbia A, Rubbia A, Rubbia A, Sakharov A D, Sakharov A D, Schwetz T, Shiozawa M [Super-Kamiokande Collaboration], Strauss T, Wiesenfeldt S, Yuanyuan Ge   +70 more
core   +1 more source

An $ep$ collider based on proton-driven plasma wakefield acceleration [PDF]

, 2014
Recent simulations have shown that a high-energy proton bunch can excite strong plasma wakefields and accelerate a bunch of electrons to the energy frontier in a single stage of acceleration. This scheme could lead to a future $ep$ collider using the LHC
Aimidula, A., Chattopadhyay, S., Mandry, S., Mete, O., Welsch, C., Wing, M., Xia, G.   +6 more
core   +2 more sources