Results 81 to 90 of about 173,486 (295)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Adoption and Diffusion of Agroecological Practices in the Horticulture of Catalonia
Agronomy, 2021 The environmental impact of conventional food production systems imposes a rapid transition towards sustainable production systems through the adoption of agroecological practices. The barriers and accelerators of the adoption of agroecological practices
Adrián Polonio Punzano +2 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
State-of-the-Art Mobile Radiation Detection Systems for Different Scenarios
Sensors, 2021 In the last decade, the development of more compact and lightweight radiation detection systems led to their application in handheld and small unmanned systems, particularly air-based platforms.
Luís Marques, Alberto Vale, Pedro Vaz
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Accelerator Memory Reuse in the Dark Silicon Era [PDF]
, 2014 Accelerators integrated on-die with General-Purpose CPUs (GP-CPUs) can yield significant performance and power improvements. Their extensive use, however, is ultimately limited by their area overhead; due to their high degree of specialization, the ...
Carloni, L.P. +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2014 The present state of development of a series of industrial superconductors is reviewed in consideration of their future applications in high field accelerator magnets, with particular attention on the material aspect.
Flükiger, R
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
MoleculesGlobal challenges in agriculture, in terms of water and nutrient loss control, require new approaches to maintaining or even increasing crop production. Promising materials, such as superabsorbent hydrogels of hybrid types obtained from natural polymers ...
Elena Manaila +3 more
doaj +1 more source