Results 81 to 90 of about 350,213 (359)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Pepper-pot emittance measurement of laser-plasma wakefield accelerated electrons

, 2009
The transverse emittance is an important parameter governing the brightness of an electron beam. Here we present the first pepper-pot measurement of the transverse emittance for a mono-energetic electron beam from a laser-plasma wakefield accelerator ...
Shanks, R. P., Welsh, G. H., Jaroszynski, D.A., M. P. Anania, Anania, M.P., Jaroszynski, D. A., Welsh, G.H., S. M. Wiggins, Cipiccia, S., Vieux, G., Gallacher, J. G., Gallacher, J.G., M. R. Islam, Ersfeld, B., Issac, R. C., R. P. Shanks, R. C. Issac, Anania, M. P., S. Cipiccia, G. Vieux, G. H. Welsh, Wiggins, S. M., Issac, R.C., J. G. Gallacher, B. Ersfeld, D. A. Jaroszynski, Islam, M. R., Islam, M.R., E. Brunetti, Shanks, R.P., Brunetti, E., Wiggins, S.M.   +31 more
core   +1 more source

State-of-the-Art Mobile Radiation Detection Systems for Different Scenarios

Sensors, 2021
In the last decade, the development of more compact and lightweight radiation detection systems led to their application in handheld and small unmanned systems, particularly air-based platforms.
Luís Marques, Alberto Vale, Pedro Vaz
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Startup Accelerators A Field Guide

, 2020
Accelerator programs have become one of the most powerful and valuable resources for entrepreneurs seeking to learn rapidly, build powerful networks, raise capital, build their startups and do this at speed and scale.
Dunn, Steve, Busulwa, Richard, Birdthistle, Naomi   +2 more
core  

Decoupling CERN accelerators

, 2018
The accelerator complex at CERN is a living system. Accelerators are being dismantled, upgraded or change their purpose. New accelerators are built. The changes do not happen overnight, but when they happen they may require profound changes across the ...
Dworak, Andrzej, Bau, Jean-Claude
core   +1 more source

Theoretical formulation of phase space microbunching instability in the presence of intrabeam scattering for single-pass or recirculation accelerators

, 2020
Microbunching instability (MBI) has been one of the most challenging issues in designs of high-brightness beam transport lines for single-pass or recirculating accelerators.
Qin, Weilun, Tsai, Cheng Ying, Zhou, Guanqun,, Fan, Kuanjun,, Wu, Juhao,, Zhou, Guanqun, Wang, Xiaofan, Fan, Kuanjun, Qin, Weilun,, Wu, Juhao, Wang, Xiaofan,, Lund University., Tsai, Cheng Ying,   +12 more
core   +1 more source

Graph analytics accelerators for cognitive systems [PDF]

, 2017
Hardware accelerators are known to be performance and power efficient. This article focuses on accelerator design for graph analytics applications, which are commonly used kernels for cognitive systems. The authors propose a templatized architecture that
Burns, S., Ozdal, M. M., Ayupov, A., Taemin Kim, Serif Yesil, Kim, T., Steven Burns, Ozcan Ozturk, Andrey Ayupov, Greth, J., Ozturk, O., Yesil, S., Muhammet Mustafa Ozdal, John Greth   +13 more
core   +1 more source

Development and performance analysis of the 200 keV Cockcroft-Walton ion accelerator

Results in Physics
This study reports the successful design, construction, and testing of a 200 keV electrostatic ion accelerator at NSTRI, emphasizing its beam transport performance and diagnostic capabilities.
H.R. Mirzaei, S.H. Sanaye, B. Yadollahzadeh, M. Shirshekan, M. Asl beigi, O. Hasanpour, Z. Riazi Mobaraki, F. Ghasemi, A. Mohammadi, M. Sadafi Biabli, A. Abbasi, M. Nazari, M. Dehghan, J. Rahighi, M. Jafarzadeh Khatibani, H. Ghods, A. Najafian   +16 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source