Results 81 to 90 of about 147,354 (313)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Ion sources for high-power hadron accelerators
, 2013 Ion sources are a critical component of all particle accelerators. They create the initial beam that is accelerated by the rest of the machine. This paper will introduce the many methods of creating a beam for high-power hadron accelerators.
Faircloth, Dan
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
European Physical Journal C: Particles and FieldsThis study explores the Chern–Simons portal model, an extension of the Standard Model that introduces a massive neutral vector boson X associated with a $$U_X(1)$$ U X ( 1 ) gauge symmetry.
Mohammad Nourbakhsh +1 more
doaj +1 more source
CAS - CERN Accelerator School: RF for Accelerators [PDF]
, 2012 These proceedings present the lectures given at the twenty-fourth specialized course organized by the CERN Accelerator School (CAS). The course was held in Ebeltoft, Denmark, from 8-17 June, 2010 in collaboration with Aarhus University, with the topic ...
Bailey, Roger
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Brief Introduction to Particle Accelerators
, 2017 This lecture is a brief introduction to charged particle accelerators. The aim is to provide the reader with basic concepts and tools needed to describe the motion of charged particles under the action of guiding and focussing fields, with an emphasis on
Tavares, P. F.,, Lund University.
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Proposing a Pattern for using Accelerating Factors, and Barriers to Formation of Entrepreneurial University in Iran [PDF]
مطالعات مدیریت راهبردی, 2017 Drucker (2010) introduces entrepreneurial society in 21st century as the substitute of social security, the great revolution of 20th century. In entrepreneurial society, universities should be innovative as every organization.
Ali Hossein Keshavarzi +2 more
doaj +2 more sources