Results 101 to 110 of about 330,152 (277)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Including Pitch Accent Optionality in Unit Selection Text-to-Speech Synthesis [PDF]
, 2008 A significant variability in pitch accent placement is found when comparing the patterns of prosodic prominence realized by different English speakers reading the same sentences. In this paper we describe a simple approach to incorporate this variability
Badino, Leonardo +2 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Post-focal and factive deaccentuation in Persian
Glossa, 2018 Two experiments were carried out to examine whether the Persian word accent is deleted in two putative deaccenting contexts, post-focal regions and presupposed embedded clauses, to the extent that accentual minimal pairs become homophonous.
Carlos Gussenhoven +2 more
doaj +2 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Foreign accent syndrome: A typological overview [PDF]
, 2014 Foreign Accent Syndrome (FAS) is a motor speech disorder which causes patients to speak their native language with an accent different from speakers belonging to the same language community: the patient lacks the ability to make the phonemic and phonetic
Bastiaanse, R. +3 more
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
L’accent français en Allemagne, l’accent allemand en France - apparition, perception et disparition d'un signe identitaire distinctif [PDF]
Synergies Pays Germanophones, 2019 L’accent est la prononciation spécifique d’un étranger qui parle une autre langue que sa langue maternelle. Même s’il s’installe dans son pays d’accueil et s’il ressemble physiquement à la majorité de ses habitants, son accent le trahira : ouvrir la ...
Dana Martin
doaj
Investigating the impact of unfamiliar speaker accent on auditory comprehension in adults with aphasia [PDF]
, 2011 Background: In an increasingly multicultural society, all individuals are likely to come into contact with speakers with unfamiliar accents. Recent figures suggest that such accent variation may be particularly apparent within the healthcare workforce ...
Bruce, C, Dunton, J, Newton, C
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source