Results 121 to 130 of about 332,652 (295)
L’anacrouse comme modèle pour appréhender le travail phonétique en langue française [PDF]
Cet article explore le parallèle que l’on peut établir entre musique et parole dans le cas de la langue française, en particulier dans le domaine du rythme. À partir de l’état des lieux qu’il dresse sur la question, il se propose de montrer que l’on peut
Cécilia Debergh
doaj
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
As a scientific discipline phono stylistics originates from the scientific studies by N.S. Trubetskoy. In the Turkic languages, phono stylistics is synharmonic.
Mahanbet Dzhusupov, Nurjamal Saparova
doaj +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Stop bashing givenness : a note on Elke Kasimir´s "questions-answers test and givenness" [PDF]
Elke Kasimir´s paper (in this volume) argues against employing the notion of Givenness in the explanation of accent assignment. I will claim that the arguments against Givenness put forward by Kasimir are inconclusive because they beg the question of the
Weskott, Thomas
core
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Japanese pitch accent in an English/Nupe/Hausa trilingual [PDF]
Pitch accent, which distinguishes words in Standard Japanese, is difficult for speakers of English to acquire. This is likely to be because pitch in English does not have lexical function.
Muradás-Taylor, Becky
core
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

