Results 111 to 120 of about 55,526 (303)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
, 1996 The subject matter of this chapter is the semantic, syntactic and discoursepragmatic background as well as the cross-linguistic behavior of types of utterance exemplified by the following English sentences […]: (1) My NECK hurts.
Sasse, Hans-Jürgen
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Accent of Masculine O-Stems in the Dialect of Komazini
Rasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2013 Neo-Štokavian dialects preserve the inherited Proto-Slavic accent paradigms relatively well. The paper discusses the accentuation of the masculine o-stems in the Neo-Štokavian dialect of Komazini and describes the changes that occurred in the accent ...
Perina Vukša Nahod
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The Unattainable Standard — Zagreb Dialect Meets Standard Croatian Accentuation
Slovene, 2018 The paper discusses the accentual accommodation by speakers of the urban dialect of Zagreb (the capital of Croatia), which has a dynamic free accent, to the Standard Croatian (Neo-Štokavian) pitch accent (with rising and falling tones). The accommodation
Mate Kapović
doaj
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
On the Accentuation of neslъ and Related Issues
Rasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2014 In a recent article of major importance (2013), Tijmen Pronk has treated the accentuation of l-participles of the type neslъ in western South Slavic. Pronk points out correctly that Dybo’s law did not shift the accent onto final jers, e.g.
Frederik Kortlandt
doaj
From Local to Global Analysis of Music Time Series [PDF]
Local and more and more global musical structure is analyzed from audio time series by time-series-event analysis with the aim of automatic sheet music production and comparison of singers. Note events are determined and classified based on local spectra,
Ligges, Uwe, Weihs, Claus
core