Results 131 to 140 of about 55,526 (303)
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Miscellaneous remarks on Balto-Slavic accentuation [PDF]
The highly successful conference on Balto-Slavic accentology organized by Mate Kapovic and Ranko Matasovic has given much food for thought. It has clarified the extent of fundamental disagreements as well as established areas of common interest where the
Kortlandt, Frederik H. H.
core
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
A number of thermometer, anthropometric and psychological characteristics of adult women of Slavic ethnicity is investigated. It is shown that mesendomorphiс index is positively correlated with body weight, massiveness of the skeleton of the lower ...
A. A. Spitsyn
doaj
Letter to Sound Rules for Accented Lexicon Compression [PDF]
This paper presents trainable methods for generating letter to sound rules from a given lexicon for use in pronouncing out-of-vocabulary words and as a method for lexicon compression.
Black, A., Lenzo, K., Pagel, V.
core +2 more sources
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
A number of thermometer, anthropometric and psychophysiological characteristics in women with anancast accentuation of character in comparison to a similar group of women without this accentuation is investigated.
A. A. Spitsyn
doaj
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source

