Results 41 to 50 of about 58,510 (335)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Emotional Determinants of Categorical Accentuation

open access: yesPsychological Topics, 2021
The presentstudy aimed to provide preliminary evidence forthe role of uncertainty related emotions in categorical accentuation. Participants had to estimate the length of lines varying in length, which depending on the conditions were or were not ...
Saša Drače, Mia Čehajić
doaj   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Issues in Balto-Slavic accentology [PDF]

open access: yes, 2010
After the very well-organized Leiden conference for which we must be grateful to Tijmen Pronk, it seems appropriate for me to review some of the papers, as I did after the previous conferences in Zagreb and Copenhagen. The aim of this review is merely to
Kortlandt, Frederik H. H.
core  

Notions and subnotions in information structure [PDF]

open access: yes, 2008
Three dimensions can be distinguished in a cross-linguistic account of information structure. First, there is the definition of the focus constituent, the part of the linguistic expression which is subject to some focus meaning.
Bolinger D.   +29 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

La phrase négative en breton : de la phonologie à la syntaxe

open access: yesLa Bretagne Linguistique, 2009
The Breton variety spoken in Malguénac (Morbihan) is a language in which stress depends on the meaning groups. The main stress emerges according to the hierarchy of information, with a peak of perceptibility on the last syllable of a group.
Erwan Le Pipec
doaj   +1 more source

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