Results 51 to 60 of about 11,340 (261)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Mental illness in the light of christian anthropology
Консультативная психология и психотерапия, 2011 Author proposes an analyze o various deviations of the spiritual and psychological spheres in the context of the Orthodox approach to fundamental stereological terms in Christian anthropology.
Egorova E.B.
doaj
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
On shortening, lengthening, and accent shifts in Slavic
Rasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2017 The paper deals with several problems of Slavic historical accentology – pretonic length in the accentual paradigm c (and b) in South and West Slavic, the neo-circumflex phenomenon (including the accent in the genitive plural), the kȍkōt ‘rooster’ type ...
Mate Kapović
doaj
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Rise and fall of vowel length in Slavic
Rasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2018 My observation that Mate Kapović’s ideas about Slavic accentuation lack a chronological perspective has evoked a furious reaction (Kortlandt 2016b: 478f., Kapović 2017).
Frederik Kortlandt
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
L’accentuation de la langue bretonne
La Bretagne Linguistique, 1986 In this study of Breton accentuation, we are not simply looking for the place of the accent (penultimate, ultieth, etc.), but for distinguishable accentual units. To what extent are accentual units not only distinguishable, but also distinctive?
Herbert Pilch
doaj +1 more source