Results 71 to 80 of about 11,340 (261)
On the Constituent Structure of Augmented Plurals in Russian
LanguagesThis article examines augmented plurals in Russian, mostly focusing on those in -ĭj- (e.g., pero/perʲja ‘feather.sg/pl’). The accentual behavior of -ĭj-plurals is sensitive to animacy: while inanimates show stem-final stress, animates appear with ...
Ora Matushansky
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
, 2023 Adolescence is a period of transition from childhood to adulthood, characterized by its peculiarities from physiological and psychological humor. At this stage, the physical and psychic development of children is greatly accelerated, interest in various things in life, desire for novelty increases, character is formed, the spiritual world is enriched ...
openaire +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The Accent of Masculine O-Stems in the Dialect of Komazini
Rasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2013 Neo-Štokavian dialects preserve the inherited Proto-Slavic accent paradigms relatively well. The paper discusses the accentuation of the masculine o-stems in the Neo-Štokavian dialect of Komazini and describes the changes that occurred in the accent ...
Perina Vukša Nahod
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Unattainable Standard — Zagreb Dialect Meets Standard Croatian Accentuation
Slovene, 2018 The paper discusses the accentual accommodation by speakers of the urban dialect of Zagreb (the capital of Croatia), which has a dynamic free accent, to the Standard Croatian (Neo-Štokavian) pitch accent (with rising and falling tones). The accommodation
Mate Kapović
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source