Results 71 to 80 of about 55,526 (303)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Temporal structures for Fast and Slow Speech Rate [PDF]
, 1998 The rhythmic component in speech synthesis often remains rather rudimentary, despite recent major efforts in the modeling of prosodic models. The European COST Action 258 has identified this problem as one of the next challenges for speech synthesis ...
Zellner, Brigitte
core +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
From Proto-Indo-European to Slavic [PDF]
, 2010 A correct evaluation of the Slavic evidence for the reconstruction of the Indo- European proto-language requires an extensive knowledge of a considerable body of data.
Kortlandt, Frederik H. H.
core
Economic Analysis and Organised Religion [PDF]
, 1995 This chapter analyses some phenomena in organized religion from the point of view of economics. It is argued that religious activity derives from the individual's quest for sense and justification that molds institutional and other features of religious ...
Jones, Eric +2 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The rhythmic dimension in fiddle-playing as the music moves to newer performing and learning contexts [PDF]
, 2008 Publisher ...
Cranitch, Matt
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Holaaa!! Writin like u talk is kewl but kinda hard 4 NLP [PDF]
, 2012 We present work in progress aiming to build tools for the normalization of User-Generated Content (UGC). As we will see, the task requires the revisiting of the initial steps of NLP processing, since UGC (micro-blog, blog, and, generally, Web 2.0 user ...
Domingo, Judit +4 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source