Results 81 to 90 of about 19,883 (299)
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Choosing, rejecting, and closely replicating, 30 years later: A commentary on Chandrashekar et al.
In a ‘very close replication’ study using the same attributes as the original, Chandrashekar et al. (2021) report a failure to replicate some choose–reject problems documented in Shafir (1993). We find that several of the original attributes have changed
Eldar Shafir, Nathan N. Cheek
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A new principle of figure-ground segregation: The accentuation [PDF]
The problem of perceptual organization was studied by Gestalt psychologists in terms of figure-ground segregation. In this paper we explore a new principle of figure-ground segregation: accentuation.
van Doorn, Andrea +8 more
core +1 more source
THE BASIC CHARACTERISTICS OF ŠTOKAVIAN PROSODY
This article discusses the basic characteristics of the development of Štokavian accentuation as well as the basic characteristics of contemporary accentuation of Štokavian dialect.
Josip Lisac
doaj
On the Constituent Structure of Augmented Plurals in Russian
This article examines augmented plurals in Russian, mostly focusing on those in -ĭj- (e.g., pero/perʲja ‘feather.sg/pl’). The accentual behavior of -ĭj-plurals is sensitive to animacy: while inanimates show stem-final stress, animates appear with ...
Ora Matushansky
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Ancient Greek Nominal Accentuation
Ancient Greek accentuation has been notoriously difficult to categorize comprehensively. We set out a new model which we believe is the first fully comprehensive account that formally treats nominal accentuation as approximations of recessive ...
Paulsen, Christian, Golston, Chris
core +1 more source

